{"id":"W4381613563","doi":"10.1101/2023.06.21.545979","title":"The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Queen's University","keywords":"Nucleoplasm; Cytoplasm; Capsid; Herpes simplex virus; Nuclear pore; Cell biology; Genome; Nuclear transport; Biology; Virology; Gene; Viral replication; Nucleus; Virus; Cell nucleus; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002793342,0.0003672865,0.0003046287,0.0001925996,0.000230253,0.0008187871,0.0004323651,0.0003941525,0.002902731],"category_scores_gemma":[0.0003869059,0.0002225712,0.0003082525,0.0001387368,0.0005356378,0.0004292433,0.0003663026,0.0005571555,0.001076682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004903923,"about_ca_system_score_gemma":0.0003784021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005922898,"about_ca_topic_score_gemma":0.0003818394,"domain_scores_codex":[0.9997146,0.00005285526,0.00004578117,0.00005255629,0.00007209014,0.00006209144],"domain_scores_gemma":[0.9997253,0.0000511804,0.00008812898,0.00006404101,0.00003077008,0.00004068447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002893168,0.00004343344,0.0005552229,0.00007894214,0.00001700888,0.000101901,0.00003472671,0.0001463034,0.9945695,0.0008613106,0.000157525,0.003144835],"study_design_scores_gemma":[0.00001602957,0.00005604365,0.001256786,0.000007022362,0.000007205146,0.0002072102,0.00001313743,0.0003705193,0.9928089,0.0000971573,0.005157452,0.000002614069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836879,0.003837215,0.006989067,0.0002745895,0.0001981192,0.00004417536,0.0007330591,0.000187819,0.004048003],"genre_scores_gemma":[0.9826921,0.001166,0.00461839,0.00007520877,0.00002017823,0.00003928266,0.0009909798,0.00008110886,0.01031667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002902731,"threshold_uncertainty_score":0.00971055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0253027034915219,"score_gpt":0.2545646038570755,"score_spread":0.2292619003655536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}