{"id":"W4381619599","doi":"10.1093/humrep/dead093.088","title":"O-074 THC reduces sperm mitochondrial membrane potential, but does not affect the acrosome reaction or in-vitro embryo developmental rates.","year":2023,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Guelph","funders":"","keywords":"Sperm; Acrosome reaction; Andrology; Fertilisation; Human fertilization; Embryo; In vitro fertilisation; Biology; Acrosome; Endocannabinoid system; Sperm motility; Cannabinoid; Embryogenesis; Pharmacology; Cell biology; Medicine; Reproductive technology; Anatomy; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001215313,0.000178506,0.0002678786,0.0001448483,0.0002024496,0.0002301303,0.0002672707,0.0003341677,0.006486653],"category_scores_gemma":[0.0002796174,0.0001369091,0.0002612327,0.00008442019,0.0002693664,0.0001835888,0.0001472434,0.0004707874,0.0005885288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003533225,"about_ca_system_score_gemma":0.0005216373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003849155,"about_ca_topic_score_gemma":0.006456924,"domain_scores_codex":[0.9998609,0.00001967333,0.00001564521,0.00002895449,0.00004140868,0.00003354394],"domain_scores_gemma":[0.9998102,0.00005166374,0.00003850573,0.00002101355,0.00004069693,0.00003808715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003869262,0.0003425344,0.0008264761,0.0003346954,0.00003986071,0.0001039571,0.00005520291,0.0000492633,0.9871317,0.0001139688,0.0004066386,0.006726381],"study_design_scores_gemma":[0.0002408326,0.006608658,0.01441298,0.00004377597,0.000124286,0.0002858159,0.0002223623,0.000472575,0.9721096,0.0001029914,0.005364181,0.0000119178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868423,0.004867412,0.001165524,0.0004710986,0.0002181308,0.0001321114,0.001358291,0.00006153196,0.004883509],"genre_scores_gemma":[0.9815964,0.002345165,0.001227427,0.0001693564,0.00003825262,0.0001025083,0.0007838202,0.00001554898,0.01372146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006486653,"threshold_uncertainty_score":0.02170002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04351717835711222,"score_gpt":0.3205130333877663,"score_spread":0.276995855030654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}