{"id":"W4381715368","doi":"10.2196/46741","title":"Recovery of Breakthrough Asthma Attacks Treated With Oral Steroids While on Monoclonal Antibody Therapy: Protocol for a Prospective Observational Study (BOOST)","year":2023,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute for Health and Care Research; Wellcome Trust","keywords":"Asthma; Medicine; Exhaled nitric oxide; Observational study; Eosinophilic; Quality of life (healthcare); Asthma attack; Intensive care medicine; Pediatrics; Immunology; Internal medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02034577,0.003548041,0.005160742,0.001686164,0.00313832,0.002260947,0.002078015,0.003747061,0.02285441],"category_scores_gemma":[0.01388002,0.001895038,0.004573298,0.002440949,0.001505663,0.002296954,0.001927876,0.002860539,0.004937086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003458697,"about_ca_system_score_gemma":0.01045502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003545343,"about_ca_topic_score_gemma":0.004147268,"domain_scores_codex":[0.9887138,0.005937319,0.001945836,0.001420894,0.0008299085,0.001152228],"domain_scores_gemma":[0.9912159,0.001230273,0.001844229,0.001224818,0.003286086,0.0011986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7578445,0.03209322,0.06367027,0.02235312,0.006243262,0.0009355643,0.001886852,0.004466143,0.003613086,0.005146777,0.05588486,0.0458623],"study_design_scores_gemma":[0.6048548,0.09080209,0.1784194,0.007035651,0.00296383,0.0003833304,0.001903084,0.005826383,0.002074366,0.004665058,0.1005188,0.000553195],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.01173837,0.0003474593,0.001899333,0.0002383218,0.0002584781,0.976131,0.008075602,0.00008123369,0.001230299],"genre_scores_gemma":[0.008184928,0.00007745301,0.001927098,0.0001763854,0.00003732888,0.9879016,0.00148705,0.000005605853,0.0002026194],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02285441,"threshold_uncertainty_score":0.1076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4215144725426884,"score_gpt":0.5772220951997116,"score_spread":0.1557076226570232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}