{"id":"W4381848342","doi":"10.1016/s2213-8587(23)00168-7","title":"People with type 1 diabetes and chronic kidney disease urgently need new therapies: a call for action","year":2023,"lang":"en","type":"article","venue":"The Lancet Diabetes & Endocrinology","topic":"Diabetes Management and Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; Sydäntutkimussäätiö; Sigrid Juséliuksen Säätiö; Novo Nordisk; KU Leuven; University of Toronto; Pfizer; Insulet Corporation; Astellas Pharma; MannKind Corporation; Diabetes Canada; Wilhelm och Else Stockmanns Stiftelse; Folkhälsanin Tutkimussäätiö; Foundation for Cardiovascular Research; Eli Lilly and Company; AstraZeneca; CSL Behring; Bayer; Gilead Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; Sanofi; Diabetestutkimussäätiö; Samfundet Folkhälsan","keywords":"Medicine; Call to action; Type 2 diabetes; Kidney disease; Diabetes mellitus; Disease; Intensive care medicine; Action (physics); MEDLINE; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002396139,0.0002094969,0.0004710221,0.0001859476,0.0001673999,0.00005004076,0.0002206835,0.00004843666,0.000157569],"category_scores_gemma":[0.0002607226,0.0001279058,0.00007050799,0.0005106691,0.0001868854,0.0000815747,0.0001478927,0.000221785,0.0001344993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005158078,"about_ca_system_score_gemma":0.0001739318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001130613,"about_ca_topic_score_gemma":0.00002547382,"domain_scores_codex":[0.9977598,0.00007080373,0.0001566252,0.0003506748,0.0002024275,0.001459712],"domain_scores_gemma":[0.9987231,0.0003465696,0.00006107133,0.0004786351,0.00007443569,0.0003161434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007823076,0.0001043253,0.6712059,0.001204157,0.001195876,0.00001786313,0.0004002354,0.00003446958,0.009961448,0.001323999,0.2610265,0.05274293],"study_design_scores_gemma":[0.008577026,0.002275739,0.5629616,0.0002457995,0.0007106895,0.000001688642,0.0002642254,0.005274598,0.002788692,0.003148521,0.4133016,0.0004498441],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9555694,0.002389911,0.00001393691,0.03982949,0.0002982735,0.001109709,0.00002080794,0.0003056716,0.0004628443],"genre_scores_gemma":[0.9830781,0.00147276,0.00009587313,0.002898288,0.001149673,0.0003207249,0.0002328413,0.00006085314,0.01069089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1522751,"threshold_uncertainty_score":0.5215847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04308128163336083,"score_gpt":0.315554828987163,"score_spread":0.2724735473538022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}