{"id":"W4381851195","doi":"10.1016/j.cbpa.2023.102353","title":"Emergence of (hydro)persulfides as suppressors of lipid peroxidation and ferroptotic cell death","year":2023,"lang":"en","type":"review","venue":"Current Opinion in Chemical Biology","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"European Research Council; Natural Sciences and Engineering Research Council of Canada; Deutsche Forschungsgemeinschaft","keywords":"Lipid peroxidation; Reactivity (psychology); Chemistry; Radical; Programmed cell death; Phospholipid; Redox; Cell biology; Cell; Biochemistry; Antioxidant; Biophysics; Apoptosis; Biology; Organic chemistry; Medicine; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006392121,0.0008801621,0.0009706236,0.001196856,0.0001499866,0.0007654428,0.0006761688,0.001220407,0.001911493],"category_scores_gemma":[0.0004612368,0.0002277936,0.0003027796,0.001245872,0.0005268963,0.00112141,0.0006424063,0.001754122,0.001341997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005300809,"about_ca_system_score_gemma":0.0007520865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004728297,"about_ca_topic_score_gemma":0.001009677,"domain_scores_codex":[0.9998667,0.00001670099,0.00001598232,0.00002601124,0.00005558714,0.00001906176],"domain_scores_gemma":[0.9997703,0.00007147896,0.00004771181,0.000008808996,0.00007253962,0.00002914296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002566785,0.00006348672,0.0001449462,0.01044301,0.00008649538,0.0002885017,0.00004985758,0.0003422218,0.01184397,0.007242143,0.02711912,0.9421197],"study_design_scores_gemma":[0.00008102114,0.0001714382,0.0006842098,0.001185977,0.0001259621,0.0007814849,0.00003592501,0.0001118069,0.005032144,0.002638995,0.9891312,0.00001971568],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003315154,0.9976985,0.0002636292,0.0003993399,0.0003518489,0.000003814744,0.00002041047,0.00001055449,0.000920403],"genre_scores_gemma":[0.002533281,0.995382,0.0002555802,0.0003593633,0.0004244826,0.000008456469,0.00005439785,0.000003163576,0.0009792898],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001911493,"threshold_uncertainty_score":0.006394565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1081398869493008,"score_gpt":0.404664834401747,"score_spread":0.2965249474524462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}