{"id":"W4381885240","doi":"10.1093/humrep/dead093.237","title":"O-196 Evidence-based management of mosaic embryos - a single Centre experience from prospective transfer and birth outcomes of 565 mosaic embryos","year":2023,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"CReATe Fertility Centre; Sunnybrook Hospital; University of Toronto","funders":"","keywords":"Mosaic; Embryo transfer; Embryo; Pregnancy; Prospective cohort study; Live birth; Obstetrics; Medicine; Retrospective cohort study; Gynecology; Biology; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020168,0.0001592046,0.0003414486,0.0001413367,0.00007967478,0.00001209302,0.0000786755,0.00005954193,0.00006253037],"category_scores_gemma":[0.0002476081,0.0001404912,0.00007970766,0.0003797782,0.0001634941,0.0001221012,0.0000444415,0.0001023048,0.000007502352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005336173,"about_ca_system_score_gemma":0.00002095188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004297862,"about_ca_topic_score_gemma":0.00002086083,"domain_scores_codex":[0.9984279,0.00004560393,0.0003558192,0.0006042817,0.0003763604,0.0001900746],"domain_scores_gemma":[0.9990441,0.00009196084,0.00009232347,0.0005825646,0.0001138867,0.00007514207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009642934,0.001090008,0.834127,0.001553208,0.0004321216,0.0001050261,0.008710698,0.0004707384,0.1322642,0.0008999662,0.001185045,0.01819769],"study_design_scores_gemma":[0.001554053,0.0004619293,0.811608,0.001401806,0.0002101935,0.000003466136,0.002225403,0.0002126256,0.1816591,0.0003522162,0.0001384826,0.0001727271],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973366,0.0007905451,0.0002625955,0.0004330287,0.0001577352,0.0006958555,0.00004408784,0.0001494523,0.0001301036],"genre_scores_gemma":[0.9979814,0.000117297,0.0005140445,0.0000259979,0.0000856449,0.00004439084,0.0000872951,0.00002064687,0.00112326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04939491,"threshold_uncertainty_score":0.5729066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05249186034363007,"score_gpt":0.295773241011689,"score_spread":0.2432813806680589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}