{"id":"W4382022477","doi":"10.1186/s12888-023-04922-6","title":"Design of a real-world, prospective, longitudinal, observational study to compare vortioxetine with other standard of care antidepressant treatments in patients with major depressive disorder: a PatientsLikeMe survey","year":2023,"lang":"en","type":"article","venue":"BMC Psychiatry","topic":"Treatment of Major Depression","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health; University Health Network","funders":"H. Lundbeck A/S; Takeda Pharmaceuticals U.S.A.","keywords":"Vortioxetine; Major depressive disorder; Observational study; Quality of life (healthcare); Anhedonia; Psychiatry; Patient satisfaction; Antidepressant; Psychology; Medicine; Clinical psychology; Cognition; Psychotherapist; Nursing; Schizophrenia (object-oriented programming); Anxiety","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009649247,0.0008308855,0.001171503,0.0009050632,0.001431046,0.001176857,0.0007517253,0.001385639,0.002199353],"category_scores_gemma":[0.007876979,0.0007894679,0.001538789,0.0009899914,0.0008071593,0.001371644,0.001159782,0.001494092,0.0006251518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001657037,"about_ca_system_score_gemma":0.003022027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004827357,"about_ca_topic_score_gemma":0.008564394,"domain_scores_codex":[0.9927716,0.004808803,0.0005287341,0.0008714923,0.0004572413,0.0005621258],"domain_scores_gemma":[0.9936537,0.001428038,0.002148822,0.000533394,0.0009703453,0.001265697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01535126,0.02161269,0.9435405,0.0004643697,0.001317491,0.000398255,0.002218281,0.0006745098,0.001183335,0.0001982386,0.001835636,0.01120547],"study_design_scores_gemma":[0.009030478,0.09875993,0.8792582,0.0001449646,0.000598014,0.0003931548,0.005344808,0.002028335,0.0004511415,0.0003027572,0.003572996,0.0001153037],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865341,0.0001694571,0.001197561,0.0001901318,0.0000435755,0.009576667,0.001801569,0.00001689245,0.0004698895],"genre_scores_gemma":[0.9555869,0.0001956206,0.006053763,0.001200427,0.0001098194,0.03317545,0.003030192,0.000009556491,0.000638348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009649247,"threshold_uncertainty_score":0.0510307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05000796247929457,"score_gpt":0.3215983603843721,"score_spread":0.2715903979050776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}