{"id":"W4382182243","doi":"10.1111/aos.15724","title":"Anti‐VEGF and steroid combination therapy relative to anti‐VEGF mono therapy for the treatment of refractory DME: A systematic review of efficacy and meta‐analysis of safety","year":2023,"lang":"en","type":"review","venue":"Acta Ophthalmologica","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"START Clinic; University of Toronto; McMaster University; Octane (Canada)","funders":"","keywords":"Medicine; Adverse effect; Combination therapy; Refractory (planetary science); Meta-analysis; Internal medicine; Ranibizumab; Oncology; Observational study; Incidence (geometry); Bevacizumab; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004945411,0.0005461853,0.007880392,0.0003150599,0.00007790629,0.00001064697,0.000188212,0.0001914695,0.00005803052],"category_scores_gemma":[0.0002304266,0.000240383,0.001943614,0.0008577243,0.0001393922,0.00004843789,0.00004201597,0.00008978701,0.000001454028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007011891,"about_ca_system_score_gemma":0.00008054243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000407907,"about_ca_topic_score_gemma":2.400174e-7,"domain_scores_codex":[0.9969125,0.0005902823,0.001422916,0.0005262618,0.0003464511,0.0002015523],"domain_scores_gemma":[0.9942177,0.002917227,0.001688742,0.0008103931,0.0002556204,0.000110296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0006174728,0.003168136,0.0001671369,0.6139798,0.3612579,0.00005560286,0.0003480682,4.923263e-7,0.00001489155,0.00009595895,0.00001476463,0.02027975],"study_design_scores_gemma":[0.00292023,0.013946,0.01388261,0.09977221,0.8648198,0.00009733656,0.0000794411,0.000008785553,0.00001258744,0.00004727242,0.004030927,0.0003827763],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01322272,0.9747355,0.000003518584,0.0001545804,0.0000233339,0.01124907,0.0005446831,0.00001377945,0.00005281893],"genre_scores_gemma":[0.04049341,0.95785,0.0000676378,0.0000339114,0.000007938694,0.001002277,0.0002675554,0.00004108851,0.0002361839],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5142076,"threshold_uncertainty_score":0.9802535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1635295203330594,"score_gpt":0.4220187025808019,"score_spread":0.2584891822477425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}