{"id":"W4382182243","doi":"10.1111/aos.15724","title":"Anti‐VEGF and steroid combination therapy relative to anti‐VEGF mono therapy for the treatment of refractory DME: A systematic review of efficacy and meta‐analysis of safety","year":2023,"lang":"en","type":"review","venue":"Acta Ophthalmologica","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"START Clinic; University of Toronto; McMaster University; Octane (Canada)","funders":"","keywords":"Medicine; Adverse effect; Combination therapy; Refractory (planetary science); Meta-analysis; Internal medicine; Ranibizumab; Oncology; Observational study; Incidence (geometry); Bevacizumab; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01201051,0.002205061,0.01705253,0.004459666,0.0005387161,0.002717873,0.001539806,0.001934142,0.002319593],"category_scores_gemma":[0.02535973,0.0012841,0.03237182,0.004537189,0.0006729009,0.001542527,0.001053327,0.001765665,0.0002262606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002116402,"about_ca_system_score_gemma":0.00266179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004339631,"about_ca_topic_score_gemma":0.009415684,"domain_scores_codex":[0.9916535,0.003951456,0.002644677,0.0007511132,0.0008113144,0.000187911],"domain_scores_gemma":[0.9821401,0.01285045,0.003245711,0.0003967179,0.001154383,0.0002125543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.003811555,0.00004562835,0.002400184,0.3766735,0.6004001,0.00009863471,0.00006621605,0.0003664789,0.0003119164,0.00009182305,0.0003159782,0.0154179],"study_design_scores_gemma":[0.001027235,0.0004010443,0.002663401,0.02053916,0.9737269,0.0000881692,0.00003384743,0.0001519854,0.0001767072,0.0001286164,0.001043278,0.00001964504],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00492215,0.9939595,0.0003004971,0.0001290811,0.0001183659,0.0001862814,0.0002041288,0.00001218356,0.000167803],"genre_scores_gemma":[0.1973959,0.7980568,0.00195441,0.0008853231,0.0002933021,0.000705927,0.0004496115,0.0000251139,0.0002335592],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01705253,"threshold_uncertainty_score":0.06351835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1635295203330594,"score_gpt":0.4220187025808019,"score_spread":0.2584891822477425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}