{"id":"W4382238612","doi":"10.7554/elife.83338.sa2","title":"Author response: Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal","funders":"Det Sundhedsvidenskabelige Fakultet, Københavns Universitet; Lundbeckfonden; H. Lundbeck A/S; Novo Nordisk Fonden; Faculty of Health and Medical Sciences, University of Western Australia; Novo Nordisk","keywords":"GLUT4; Skeletal muscle; Glucose transporter; Microtubule; Nocodazole; Glucose uptake; Cell biology; Kinesin; Biology; Insulin; Insulin resistance; Internal medicine; Endocrinology; Cell; Cytoskeleton; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001730602,0.0005223719,0.0005076162,0.001016274,0.0009901371,0.001823654,0.0008843215,0.00249655,0.1701855],"category_scores_gemma":[0.01378334,0.0002165459,0.0002375904,0.0006376341,0.000676612,0.0009861515,0.00117673,0.001726415,0.08102206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009311657,"about_ca_system_score_gemma":0.002397751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002240292,"about_ca_topic_score_gemma":0.006709187,"domain_scores_codex":[0.9984841,0.0001675271,0.00007636435,0.0001587422,0.0009892053,0.0001239583],"domain_scores_gemma":[0.9879567,0.001543027,0.0005981366,0.0004296684,0.007513511,0.001958903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001648155,0.00002162755,0.0006134097,0.0003948346,0.00001315044,0.0007224343,0.0001583703,0.000146333,0.005693372,0.0008623528,0.9594044,0.03180501],"study_design_scores_gemma":[0.00003108136,0.000041678,0.002734216,0.00009336681,0.000009984766,0.0005402727,0.000345805,0.0002036893,0.002478142,0.0007153956,0.992784,0.00002239381],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"other","genre_scores_codex":[0.0303401,0.01079961,0.006506468,0.337502,0.4270859,0.0006804555,0.005797993,0.004487447,0.1768],"genre_scores_gemma":[0.04250292,0.005465778,0.001950586,0.01351138,0.01972668,0.0001017398,0.001893776,0.0008164935,0.9140306],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.1701855,"threshold_uncertainty_score":0.5693274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02732290274968113,"score_gpt":0.3184178915628031,"score_spread":0.291094988813122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}