{"id":"W4382344637","doi":"10.1136/bmjopen-2022-069708","title":"Non-inferiority trial of a shorter (7 days) compared with a longer (14 days) duration of antimicrobial therapy for the treatment of bacteraemic urinary sepsis, measured by microbiological success after the completion of therapy: a substudy protocol for the Bacteraemia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) multicentre randomised controlled trial","year":2023,"lang":"en","type":"article","venue":"BMJ Open","topic":"Urinary Tract Infections Management","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Health and Medical Research Council; Medical Research Council","keywords":"Medicine; Sepsis; Antimicrobial; Urinary system; Duration (music); Internal medicine; Clinical trial; Intensive care medicine; Emergency medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0133894,0.003161561,0.005155567,0.0008361214,0.001133438,0.002280961,0.001340342,0.004798076,0.01377671],"category_scores_gemma":[0.01586382,0.001115698,0.006546918,0.0007165891,0.001845127,0.001920047,0.001320526,0.003718058,0.001732354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001555028,"about_ca_system_score_gemma":0.002308465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001229134,"about_ca_topic_score_gemma":0.001854516,"domain_scores_codex":[0.9888132,0.008546767,0.0008321568,0.0006339875,0.0006047194,0.0005691344],"domain_scores_gemma":[0.9917687,0.00363811,0.002124101,0.0007303381,0.0007105636,0.001028141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9906511,0.00129065,0.0001985178,0.001747226,0.00159868,0.00002255251,0.00006557282,0.0001678639,0.0005368755,0.0001843156,0.0005022603,0.003034442],"study_design_scores_gemma":[0.9767056,0.02054196,0.0005201093,0.0001989718,0.0008923414,0.00001302635,0.00001767279,0.0001817907,0.0001212185,0.0002066424,0.0005883529,0.00001228526],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.7543576,0.02873481,0.005945764,0.004690367,0.006647048,0.183746,0.005321451,0.0004519837,0.01010506],"genre_scores_gemma":[0.7197554,0.006611582,0.008960139,0.003809576,0.002267758,0.2492408,0.002214852,0.00008048678,0.007059464],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.01377671,"threshold_uncertainty_score":0.07081079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1186359267207026,"score_gpt":0.4326908130695458,"score_spread":0.3140548863488432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}