{"id":"W4382344916","doi":"10.26508/lsa.202302196","title":"MAP4K4 regulates forces at cell–cell and cell–matrix adhesions to promote collective cell migration","year":2023,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Genentech; McGill University","keywords":"Cell biology; Cell migration; Adherens junction; Cell adhesion; Focal adhesion; Extracellular matrix; Biology; Cell; Regulator; Actin cytoskeleton; Cytoskeleton; Cadherin; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001289191,0.0004509831,0.0001821515,0.0004211939,0.0002719562,0.0003465054,0.000296811,0.0002574179,0.001212846],"category_scores_gemma":[0.0001541867,0.0002092545,0.0002760889,0.0001526386,0.000290483,0.0003073695,0.0003361675,0.0003364718,0.0003694959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004922037,"about_ca_system_score_gemma":0.0002964739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007525997,"about_ca_topic_score_gemma":0.0006820016,"domain_scores_codex":[0.9999068,0.00001358715,0.000005597598,0.00001735375,0.00002042043,0.00003628301],"domain_scores_gemma":[0.9999129,0.000008121711,0.00002746544,0.000009459487,0.00001328405,0.00002889696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001272556,0.00003223519,0.000892652,0.00002688904,0.000008322141,0.00005423086,0.00001085687,0.0002851908,0.9968441,0.000300764,0.00005505924,0.001362465],"study_design_scores_gemma":[0.00004305332,0.0001677037,0.03382584,0.000006997816,0.00002657041,0.0002103471,0.00005662826,0.005322199,0.9575804,0.0004652597,0.002282927,0.00001206371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945275,0.000718449,0.002910576,0.00008353016,0.00001562088,0.00001538255,0.0001068009,0.00006680571,0.001555241],"genre_scores_gemma":[0.9970385,0.000271496,0.001081632,0.00001405358,0.000004361375,0.00002291384,0.00008503351,0.00001088032,0.001471078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001212846,"threshold_uncertainty_score":0.004057348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01102211037930287,"score_gpt":0.2616963479480667,"score_spread":0.2506742375687638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}