{"id":"W4382369490","doi":"10.3390/pharmaceutics15071844","title":"Localized Drug Delivery Systems: An Update on Treatment Options for Head and Neck Squamous Cell Carcinomas","year":2023,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Radiation therapy; Head and neck squamous-cell carcinoma; Head and neck cancer; Transdermal; Drug delivery; Immunotherapy; Cancer; Chemotherapy; Drug; Oncology; Head and neck; Disease; Internal medicine; Intensive care medicine; Surgery; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000396554,0.0006986847,0.001150428,0.002295981,0.0002445425,0.0007983144,0.0005579769,0.000823403,0.004592081],"category_scores_gemma":[0.0006180569,0.0002536959,0.0008122354,0.001905423,0.0002922063,0.001105165,0.0004143608,0.001387776,0.001299458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004444293,"about_ca_system_score_gemma":0.0007465265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001242551,"about_ca_topic_score_gemma":0.002323871,"domain_scores_codex":[0.9997945,0.00003512515,0.00003875646,0.00003164697,0.00008380445,0.00001615334],"domain_scores_gemma":[0.9997208,0.0001633936,0.00003640567,0.00000616157,0.00006141187,0.00001193646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006955582,0.00009009668,0.0001205964,0.0448567,0.0001110931,0.0002187112,0.00009323047,0.0003857576,0.002390232,0.003341623,0.0302886,0.9180338],"study_design_scores_gemma":[0.00001570475,0.000115083,0.0005006236,0.006334595,0.0001493243,0.001147215,0.00004317615,0.00009549986,0.0004562193,0.0007576884,0.9903708,0.00001405258],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001423672,0.9985685,0.00008804262,0.0001326013,0.0001397199,0.000007074386,0.00002341226,0.000006033117,0.0008921787],"genre_scores_gemma":[0.0004972575,0.9986999,0.0001596912,0.0001223179,0.00006545555,0.000006750027,0.00002793409,0.000001407007,0.0004191943],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004592081,"threshold_uncertainty_score":0.01536208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.218516354459027,"score_gpt":0.4471611379840435,"score_spread":0.2286447835250165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}