{"id":"W4382369490","doi":"10.3390/pharmaceutics15071844","title":"Localized Drug Delivery Systems: An Update on Treatment Options for Head and Neck Squamous Cell Carcinomas","year":2023,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Radiation therapy; Head and neck squamous-cell carcinoma; Head and neck cancer; Transdermal; Drug delivery; Immunotherapy; Cancer; Chemotherapy; Drug; Oncology; Head and neck; Disease; Internal medicine; Intensive care medicine; Surgery; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002150144,0.0005763134,0.002142722,0.0002034578,0.0002155926,0.00003943736,0.0000992141,0.0001596326,0.000009543385],"category_scores_gemma":[0.00001704223,0.0004137512,0.0003607914,0.0002062637,0.00006550062,0.00003851114,0.00005504998,0.0002638331,0.00009835562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005998185,"about_ca_system_score_gemma":0.0003983518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001353016,"about_ca_topic_score_gemma":0.00005341693,"domain_scores_codex":[0.9979857,0.0001383503,0.0005880226,0.0005652998,0.0002112701,0.0005113304],"domain_scores_gemma":[0.9985806,0.0003448675,0.0001804301,0.0003905007,0.00009963636,0.000403984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004583675,0.001198243,0.00005543138,0.1571177,0.001273502,0.0003001422,0.0009940435,0.00002746283,0.00000481786,0.0001548055,0.01007909,0.8283364],"study_design_scores_gemma":[0.003635799,0.0008262356,0.000002030677,0.004876013,0.006779246,0.00003772292,0.0001271196,0.0008473603,0.00001878012,0.000003196709,0.9825016,0.0003449171],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001401336,0.9929205,0.000008532597,0.0001193063,0.0007775188,0.003479615,0.0008018418,0.0001814352,0.0003098718],"genre_scores_gemma":[0.0005160525,0.994574,0.000137596,0.0002177489,0.0005960553,0.001053214,0.000496714,0.0001411342,0.002267542],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9724225,"threshold_uncertainty_score":0.9998314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.218516354459027,"score_gpt":0.4471611379840435,"score_spread":0.2286447835250165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}