{"id":"W4382397205","doi":"10.1038/d41586-023-02051-4","title":"How genetically modified mosquitoes could eradicate malaria","year":2023,"lang":"en","type":"article","venue":"Nature","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"World Federation of Science Journalists","funders":"","keywords":"Malaria; Gene drive; Biology; Genetically modified organism; Biotechnology; Gene; Virology; Genetics; CRISPR; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002279735,0.000359862,0.0001632149,0.0001551336,0.0001929678,0.0006257521,0.0002423941,0.000587557,0.001397687],"category_scores_gemma":[0.0001710805,0.0001784902,0.0001940436,0.00009325676,0.0005255097,0.0005343217,0.0002385062,0.001162589,0.0003333798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004080095,"about_ca_system_score_gemma":0.000339837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005566473,"about_ca_topic_score_gemma":0.0008410167,"domain_scores_codex":[0.999925,0.00001298448,0.000004464234,0.00001536245,0.00002667301,0.00001552512],"domain_scores_gemma":[0.9999605,0.000008538831,0.000008160609,0.000007125389,0.000006292333,0.000009338552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001764516,0.0000430079,0.0004099534,0.000140909,0.00004173198,0.0002913341,0.00005130449,0.001343197,0.9178013,0.05427873,0.002993124,0.02242905],"study_design_scores_gemma":[0.00006952083,0.0002909648,0.001699414,0.0000384924,0.00009604054,0.0007220855,0.00009065894,0.006932357,0.8460085,0.02057368,0.1234445,0.0000338991],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6418108,0.02370987,0.1838782,0.02780855,0.006499266,0.0002874103,0.001374477,0.00243787,0.1121936],"genre_scores_gemma":[0.9208618,0.01090492,0.03720204,0.001348043,0.0001860433,0.00006002919,0.0002422772,0.000102372,0.02909248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001397687,"threshold_uncertainty_score":0.004675746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007836938084488465,"score_gpt":0.2876889762194946,"score_spread":0.2798520381350061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}