{"id":"W4382518065","doi":"10.1016/j.joca.2023.05.016","title":"BMP signaling: A significant player and therapeutic target for osteoarthritis","year":2023,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Science and Engineering Research Board; Ministry of Education, India; Department of Science and Technology, Ministry of Science and Technology, India; Versus Arthritis; Department of Biotechnology, Ministry of Science and Technology, India; Sleep Research Society Foundation; University Canada West; Wellcome Trust; Shastri Indo-Canadian Institute","keywords":"Pathogenesis; Osteoarthritis; Medicine; Bone morphogenetic protein; Signal transduction; Bone morphogenetic protein 2; Cartilage; Cancer research; Pathology; Biology; Cell biology; Anatomy; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004647625,0.0004712218,0.0005577113,0.000745535,0.0003795128,0.001555483,0.000341455,0.0007614031,0.00686463],"category_scores_gemma":[0.0002672967,0.000155253,0.000307016,0.0006661891,0.0007742742,0.0009743316,0.0008574793,0.001745777,0.001517154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004677853,"about_ca_system_score_gemma":0.001191854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006072431,"about_ca_topic_score_gemma":0.001343969,"domain_scores_codex":[0.9998149,0.00002333424,0.00001238786,0.00001864297,0.0000919697,0.00003871259],"domain_scores_gemma":[0.9998754,0.00001706026,0.00002407825,0.000005037813,0.00003764136,0.00004069954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001458159,0.0003095782,0.002960008,0.004203489,0.0001698693,0.001113439,0.0001999364,0.0004211534,0.2142584,0.06679896,0.05620766,0.6518994],"study_design_scores_gemma":[0.0002230921,0.001192929,0.0125143,0.001565362,0.0003412426,0.00345808,0.001162206,0.000875317,0.06430384,0.02785201,0.8864527,0.00005907356],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02900034,0.9011565,0.005738837,0.02943205,0.004324965,0.00007378298,0.0008763559,0.0001457818,0.02925132],"genre_scores_gemma":[0.1681849,0.7921529,0.006031782,0.005273384,0.002905944,0.00006548084,0.0005621657,0.00003471498,0.02478878],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00686463,"threshold_uncertainty_score":0.02296448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.019384375536654,"score_gpt":0.2547098973228903,"score_spread":0.2353255217862363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}