{"id":"W4382518065","doi":"10.1016/j.joca.2023.05.016","title":"BMP signaling: A significant player and therapeutic target for osteoarthritis","year":2023,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Science and Engineering Research Board; Ministry of Education, India; Department of Science and Technology, Ministry of Science and Technology, India; Versus Arthritis; Department of Biotechnology, Ministry of Science and Technology, India; Sleep Research Society Foundation; University Canada West; Wellcome Trust; Shastri Indo-Canadian Institute","keywords":"Pathogenesis; Osteoarthritis; Medicine; Bone morphogenetic protein; Signal transduction; Bone morphogenetic protein 2; Cartilage; Cancer research; Pathology; Biology; Cell biology; Anatomy; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003213584,0.0003746576,0.0006108628,0.000203776,0.0003410002,0.0001541212,0.00006491313,0.0002071035,0.0001328273],"category_scores_gemma":[0.00004813519,0.0003556234,0.0001794002,0.0002708034,0.0001749201,0.0001503696,0.00007025683,0.0001587658,0.00006727952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002284143,"about_ca_system_score_gemma":0.0000662533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002990913,"about_ca_topic_score_gemma":0.00002761351,"domain_scores_codex":[0.9978673,0.00005575108,0.0004004526,0.000671192,0.0003003751,0.0007048826],"domain_scores_gemma":[0.9989429,0.0001593814,0.00008575551,0.0003050072,0.000106726,0.0004002272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004827292,0.00007339173,0.001841968,0.0001627113,0.00001745184,0.0004672449,0.0007171945,0.000001070086,0.657832,0.001889497,0.0004212603,0.3360935],"study_design_scores_gemma":[0.04345506,0.03875348,0.001096094,0.00146917,0.0006866592,0.001248166,0.004436078,0.00009322238,0.7513552,0.008936228,0.1467722,0.001698441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845493,0.01091876,0.0000399751,0.0007895148,0.0002976285,0.001705275,0.0002313378,0.0003146832,0.001153508],"genre_scores_gemma":[0.9947091,0.0006963323,0.0007679555,0.0004689464,0.0002633059,0.0005664672,0.0002293207,0.000091669,0.002206891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3343951,"threshold_uncertainty_score":0.9998896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.019384375536654,"score_gpt":0.2547098973228903,"score_spread":0.2353255217862363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}