{"id":"W4382519661","doi":"10.1016/b978-0-32-390644-9.00088-3","title":"Crystallization: A Tool for Asymmetric Synthesis and Isolation","year":2023,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Molecular spectroscopy and chirality","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Racemization; Crystallization; Enantiopure drug; Diastereomer; Chiral resolution; Atropisomer; Materials science; Chemistry; Organic chemistry; Enantioselective synthesis; Enantiomer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001532911,0.0003133255,0.0003737842,0.0001205927,0.000136244,0.00007658257,0.0001393384,0.0004080264,0.0002451914],"category_scores_gemma":[0.0001195622,0.0003294529,0.000202079,0.00001948966,0.00005421277,0.00002811847,0.0000736227,0.000205371,0.00003041215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006726351,"about_ca_system_score_gemma":0.0000551857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":2.65969e-7,"about_ca_topic_score_gemma":0.000006142208,"domain_scores_codex":[0.9987317,0.000007761727,0.0003561662,0.0004652754,0.0002275431,0.0002115946],"domain_scores_gemma":[0.9990587,0.0001802472,0.0002163245,0.0004031937,0.00007494664,0.00006663407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004044492,0.000006970931,0.0000144806,0.0009840443,0.0001888138,0.00001101641,0.00006096254,7.203145e-7,0.001819846,0.03142975,0.0001491495,0.9652938],"study_design_scores_gemma":[0.0002806526,0.00002842875,0.00001303964,0.00049115,0.0003565896,0.000008636598,0.000003966662,0.0001345328,0.007396337,0.03133944,0.9593659,0.0005813177],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.00006576084,0.0003811397,0.0006361359,0.00004468475,0.00009296432,0.0002981212,0.0001605425,0.0001500706,0.9981706],"genre_scores_gemma":[0.001924297,0.0001423147,0.0008227676,0.00007935562,0.000330462,0.0001583218,0.0001026425,0.0001240481,0.9963158],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.9647125,"threshold_uncertainty_score":0.9999158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01572327624379415,"score_gpt":0.2450204485189397,"score_spread":0.2292971722751455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}