{"id":"W4382538536","doi":"10.3389/fmed.2023.1185523","title":"Comparative effectiveness of biologics for patients with moderate-to-severe psoriasis and special area involvement: week 12 results from the observational Psoriasis Study of Health Outcomes (PSoHO)","year":2023,"lang":"en","type":"article","venue":"Frontiers in Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dermatrials Research","funders":"Eli Lilly and Company","keywords":"Medicine; Ixekizumab; Psoriasis; Secukinumab; Ustekinumab; Dermatology; Internal medicine; Adalimumab; Physical therapy; Psoriatic arthritis; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01116145,0.0005243366,0.001868026,0.0006461374,0.000324378,0.0007767905,0.0006269165,0.0008457301,0.002709267],"category_scores_gemma":[0.01307029,0.0002904747,0.004260358,0.0007049241,0.000345389,0.0007185123,0.0006542132,0.001168129,0.0002322699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004393985,"about_ca_system_score_gemma":0.0004621981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000711044,"about_ca_topic_score_gemma":0.001080954,"domain_scores_codex":[0.9918594,0.005264932,0.0009670305,0.0007513235,0.0008046547,0.0003526684],"domain_scores_gemma":[0.9818911,0.008032254,0.006678673,0.001453031,0.0008182249,0.001126744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5146239,0.003553243,0.4124867,0.001470214,0.02312982,0.0001059518,0.0003397214,0.001664751,0.001678008,0.0001802064,0.001292813,0.03947465],"study_design_scores_gemma":[0.04811959,0.07334852,0.8587062,0.0002703702,0.01257396,0.0004326742,0.0002974701,0.002149964,0.001327904,0.0005174158,0.002165811,0.00009012044],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932849,0.003339805,0.0003019836,0.0001288179,0.00003121398,0.0001387576,0.001833596,0.000008918257,0.0009318272],"genre_scores_gemma":[0.996896,0.0005246908,0.0003445228,0.00008742408,0.00003633886,0.0001549637,0.001641404,0.000004571002,0.0003100919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01116145,"threshold_uncertainty_score":0.05902809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07985886528838769,"score_gpt":0.2968431272682186,"score_spread":0.2169842619798309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}