{"id":"W4382630753","doi":"10.1097/sla.0000000000005973","title":"Propranolol Normalizes Metabolomic Signatures Thereby Improving Outcomes After Burn","year":2023,"lang":"en","type":"article","venue":"Annals of Surgery","topic":"Burn Injury Management and Outcomes","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Hospital; McMaster University; Hamilton Health Sciences","funders":"Canadian Institutes of Health Research","keywords":"Propranolol; Medicine; Internal medicine; Endocrinology; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007670814,0.0002072229,0.000668354,0.0005093235,0.00004564132,0.00002116456,0.0001049242,0.0001112917,0.0003144642],"category_scores_gemma":[0.0003000331,0.0001460863,0.0004710066,0.0004455566,0.00008246152,0.0002009176,0.0001048559,0.0001627802,0.0001559195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004704596,"about_ca_system_score_gemma":0.0000470731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004311726,"about_ca_topic_score_gemma":0.000004021118,"domain_scores_codex":[0.9984677,0.00004738928,0.0004557073,0.0002446352,0.000354671,0.0004298725],"domain_scores_gemma":[0.9989402,0.0003203173,0.000165825,0.0003637291,0.0001259336,0.00008404716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006592111,0.0001193721,0.8932371,0.0006354774,0.0006609597,0.0002146093,0.0002593056,0.000003295175,0.005421279,0.0002484771,0.03804324,0.06049768],"study_design_scores_gemma":[0.0002941373,0.00003975026,0.969619,0.000098037,0.0001117533,0.000002395917,0.0001134183,0.00004210003,0.01909338,0.0003637299,0.01001306,0.0002092518],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898717,0.002134318,0.000009512967,0.006069356,0.0004356546,0.0002868775,0.00001564309,0.0002280137,0.0009489402],"genre_scores_gemma":[0.9919494,0.0006799676,0.00004865786,0.002432981,0.0001118718,0.00004569718,0.00002483741,0.0000359685,0.004670657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07638189,"threshold_uncertainty_score":0.5957226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.128207991320858,"score_gpt":0.3423643736045039,"score_spread":0.2141563822836459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}