{"id":"W4382632362","doi":"10.1172/jci.insight.163297","title":"Prevention of atrial fibrillation after open-chest surgery with extracellular vesicle therapy","year":2023,"lang":"en","type":"article","venue":"JCI Insight","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; McGill University; Montreal Heart Institute; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Ottawa","keywords":"Atrial fibrillation; Extracellular vesicles; Medicine; Cardiology; Internal medicine; Extracellular vesicle; Chemistry; Microvesicles; Biology; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002796785,0.0001412707,0.0001816,0.00006894247,0.00004835083,0.00003915444,0.0001732049,0.0001216573,0.00007266798],"category_scores_gemma":[0.00005186499,0.0001235386,0.0001658109,0.000256963,0.00007164197,0.0000185138,0.0001167378,0.00004704401,0.00003318321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001154065,"about_ca_system_score_gemma":0.0001290784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001006239,"about_ca_topic_score_gemma":0.00001190023,"domain_scores_codex":[0.9989195,0.0001103883,0.0002751919,0.0003246671,0.0001814677,0.0001887982],"domain_scores_gemma":[0.9992195,0.00003470937,0.000152725,0.0004482965,0.00007576129,0.0000689429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002624366,0.0001174093,0.04899859,0.00006999069,0.0001686835,0.00005504149,0.0001432797,0.0004222066,0.9112154,0.0001169882,0.002257177,0.03381088],"study_design_scores_gemma":[0.001693849,0.0005270706,0.0498968,0.00007178299,0.00004622847,0.000009010098,0.000051568,0.000170984,0.7642607,0.0003292207,0.1825492,0.0003935749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933765,0.005060981,0.000455983,0.00006357612,0.0001360203,0.0003921367,0.00001337808,0.00002551486,0.0004759104],"genre_scores_gemma":[0.9966467,0.0006773927,0.000399892,0.00002280354,0.0004019109,0.00002057556,0.0002650649,0.00003885092,0.001526807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.180292,"threshold_uncertainty_score":0.503776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02745591311858965,"score_gpt":0.2756189254064151,"score_spread":0.2481630122878255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}