{"id":"W4382722102","doi":"10.3390/v15071473","title":"Modulation of Reoviral Cytolysis (II): Cellular Stemness","year":2023,"lang":"en","type":"article","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"University of Toronto; Canadian Institutes of Health Research; Dalhousie University","keywords":"Oncolytic virus; Induced pluripotent stem cell; Cytolysis; Biology; Embryonic stem cell; Cancer cell; Stem cell; Cell biology; Tropism; Cancer stem cell; Cancer research; Immune system; Cancer; Immunology; In vitro; Cytotoxic T cell; Virus; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002624828,0.0001009333,0.0001266894,0.0001174226,0.00008711104,0.000009808394,0.0001961415,0.00009564493,0.00007142359],"category_scores_gemma":[0.00004430788,0.0000977003,0.00008067767,0.0003432106,0.00006775351,0.000004746024,0.0001345569,0.000048332,0.00006086169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008456555,"about_ca_system_score_gemma":0.00005258231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003363563,"about_ca_topic_score_gemma":0.0000397931,"domain_scores_codex":[0.9990675,0.00008329625,0.0001802839,0.0002410667,0.0002177379,0.0002100964],"domain_scores_gemma":[0.9994007,0.00001208587,0.00006001563,0.0004070659,0.0000745178,0.00004559992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000413393,0.00003407293,0.001534048,0.0000179234,0.00005117634,0.000002569374,0.00004104062,0.0006555813,0.9931018,0.00002807402,0.0008365753,0.003283775],"study_design_scores_gemma":[0.0002977698,0.0008012737,0.001390348,0.000006710503,0.000008251749,5.090585e-7,0.00003843289,0.000382638,0.9917001,0.00007356262,0.005191543,0.0001088303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988999,0.0003467269,0.0001619173,0.00005139984,0.00007144745,0.0001251476,0.00003698135,0.00003220724,0.0002742067],"genre_scores_gemma":[0.9984606,0.0001724275,0.00006077181,0.00008899497,0.0001358993,0.00001988174,0.0001165079,0.00002617799,0.0009187757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004354968,"threshold_uncertainty_score":0.3984103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03754082835116819,"score_gpt":0.3143442989183408,"score_spread":0.2768034705671726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}