{"id":"W4382726918","doi":"10.3390/neuroglia4030012","title":"A Human Microglial Cell Line Expresses γ-Aminobutyric Acid (GABA) Receptors and Responds to GABA and Muscimol by Increasing Production of IL-8","year":2023,"lang":"en","type":"article","venue":"Neuroglia","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; National Research Council Canada; National Institute for Nanotechnology","funders":"National Research Council Canada","keywords":"Muscimol; Bicuculline; GABAA receptor; Chemistry; GABA receptor; gamma-Aminobutyric acid; GABAergic; Receptor; Pharmacology; Internal medicine; Endocrinology; Biochemistry; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003408244,0.0009196965,0.0005896413,0.0004981067,0.0007113938,0.0003451724,0.0004781507,0.000584734,0.003447957],"category_scores_gemma":[0.0001146615,0.0003165757,0.0007276505,0.0009552044,0.0002602088,0.0001645622,0.0003449721,0.0007492336,0.00187411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003322968,"about_ca_system_score_gemma":0.0003496902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002097741,"about_ca_topic_score_gemma":0.003573768,"domain_scores_codex":[0.9992865,0.00008559715,0.00009916705,0.0001537983,0.0002305839,0.0001444019],"domain_scores_gemma":[0.9998474,0.00002293601,0.00003047426,0.00003225421,0.00004569429,0.00002123661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002452241,0.0001907589,0.0008614954,0.0001544736,0.0000185031,0.0002729117,0.0000839181,0.0001377282,0.9946619,0.0001939296,0.0005562001,0.002623041],"study_design_scores_gemma":[0.0001993335,0.001565566,0.01236498,0.00006032802,0.0001144753,0.001509108,0.0001794003,0.003276845,0.9624426,0.0002047596,0.01804411,0.00003851769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.947309,0.006619693,0.02103598,0.0006427923,0.0003928239,0.0007922111,0.008892928,0.0006638516,0.01365072],"genre_scores_gemma":[0.9167846,0.004945403,0.04064349,0.0005055137,0.0001728489,0.002019024,0.01771927,0.00009667183,0.0171131],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003447957,"threshold_uncertainty_score":0.01153451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02793262983169596,"score_gpt":0.2675454819643639,"score_spread":0.2396128521326679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}