{"id":"W4382726918","doi":"10.3390/neuroglia4030012","title":"A Human Microglial Cell Line Expresses γ-Aminobutyric Acid (GABA) Receptors and Responds to GABA and Muscimol by Increasing Production of IL-8","year":2023,"lang":"en","type":"article","venue":"Neuroglia","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; National Research Council Canada; National Institute for Nanotechnology","funders":"National Research Council Canada","keywords":"Muscimol; Bicuculline; GABAA receptor; Chemistry; GABA receptor; gamma-Aminobutyric acid; GABAergic; Receptor; Pharmacology; Internal medicine; Endocrinology; Biochemistry; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003180277,0.0002381465,0.0002291907,0.0003828663,0.0003197614,0.0001159199,0.0001781357,0.00007012986,0.00002826639],"category_scores_gemma":[0.001028572,0.0002489876,0.00003927923,0.0007396003,0.0001074235,0.0002883993,0.0001918705,0.0001875211,0.00003672785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001127741,"about_ca_system_score_gemma":0.00002342983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006410745,"about_ca_topic_score_gemma":0.000005299787,"domain_scores_codex":[0.9976979,0.0003910018,0.0004197185,0.0008063677,0.0003792141,0.0003057506],"domain_scores_gemma":[0.9990901,0.0001473032,0.00017859,0.0003309314,0.00006618318,0.000186847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008430512,0.00004630167,0.00007536075,0.00005000386,9.073451e-7,0.00001941073,0.0003277717,0.00002541998,0.9944952,0.0000916965,0.003971625,0.0008120418],"study_design_scores_gemma":[0.0003853605,0.0003959683,0.0003999781,0.00001666098,0.0000109349,0.00004782496,0.00004096533,0.0001920562,0.9913099,0.00004374627,0.006965682,0.0001909058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972944,0.00001787361,0.0000259977,0.0009066684,0.0008033531,0.0004854864,0.0000901509,0.0002589696,0.0001171393],"genre_scores_gemma":[0.9954681,0.0001179672,0.0002111694,0.0005841608,0.0001476113,0.00003158057,0.000009933543,0.00005102335,0.003378416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003261277,"threshold_uncertainty_score":0.9999962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02793262983169596,"score_gpt":0.2675454819643639,"score_spread":0.2396128521326679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}