{"id":"W4382795970","doi":"10.1002/clt2.12272","title":"In chronic spontaneous urticaria soluble FcεRI is elevated and linked to atopy and chronic inducible urticaria","year":2023,"lang":"en","type":"letter","venue":"Clinical and Translational Allergy","topic":"Urticaria and Related Conditions","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"AllerGen; University of Toronto","funders":"Florida Agricultural Experiment Station; Genentech; Parkinson Study Group; Celldex Therapeutics; Galderma; Aimmune Therapeutics; Thermo Fisher Scientific; AstraZeneca; CSL Behring; Octapharma; AbbVie; Beiersdorf; Sanofi; Roche; Celgene; UCB Pharma; Regeneron Pharmaceuticals; Novartis; Amgen; Pfizer; Deutsche Forschungsgemeinschaft; Chiesi España; GlaxoSmithKline","keywords":"Medicine; Immunoglobulin E; Sensitization; Autoantibody; Atopy; Allergy; Immunology; Biomarker; Clinical significance; Antibody; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001186999,0.0004536609,0.0005871654,0.001013045,0.000385293,0.0008674126,0.0007397132,0.001673269,0.006766437],"category_scores_gemma":[0.006468363,0.0002276929,0.0001974559,0.0007384088,0.0004782104,0.0008664375,0.0005520194,0.001353339,0.001531473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001982761,"about_ca_system_score_gemma":0.0002285195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007689862,"about_ca_topic_score_gemma":0.0008040427,"domain_scores_codex":[0.9993138,0.0001591388,0.0001436642,0.0001535676,0.0001382092,0.000091593],"domain_scores_gemma":[0.9958366,0.002180218,0.0006086244,0.0001756827,0.0008370255,0.0003617495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.004500673,0.0004490259,0.3291601,0.0028963,0.0004039738,0.0582955,0.0005706663,0.0002259539,0.007195746,0.001198164,0.4455603,0.1495436],"study_design_scores_gemma":[0.00043955,0.0008211648,0.3956555,0.002634419,0.0005193801,0.2108843,0.0009678048,0.002166657,0.004544733,0.001847713,0.379372,0.0001468065],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5488108,0.1310867,0.007175434,0.1648059,0.1173305,0.0002883034,0.0137467,0.000571335,0.01618421],"genre_scores_gemma":[0.794163,0.02659929,0.002116224,0.03798449,0.1245745,0.00007246226,0.005345137,0.0001211872,0.009023734],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006766437,"threshold_uncertainty_score":0.022636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04436404195791082,"score_gpt":0.3249015798311541,"score_spread":0.2805375378732433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}