{"id":"W4382795970","doi":"10.1002/clt2.12272","title":"In chronic spontaneous urticaria soluble FcεRI is elevated and linked to atopy and chronic inducible urticaria","year":2023,"lang":"en","type":"letter","venue":"Clinical and Translational Allergy","topic":"Urticaria and Related Conditions","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"AllerGen; University of Toronto","funders":"Florida Agricultural Experiment Station; Genentech; Parkinson Study Group; Celldex Therapeutics; Galderma; Aimmune Therapeutics; Thermo Fisher Scientific; AstraZeneca; CSL Behring; Octapharma; AbbVie; Beiersdorf; Sanofi; Roche; Celgene; UCB Pharma; Regeneron Pharmaceuticals; Novartis; Amgen; Pfizer; Deutsche Forschungsgemeinschaft; Chiesi España; GlaxoSmithKline","keywords":"Medicine; Immunoglobulin E; Sensitization; Autoantibody; Atopy; Allergy; Immunology; Biomarker; Clinical significance; Antibody; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002593204,0.0004025315,0.0008623663,0.0002942899,0.0001472137,0.000060227,0.0001069683,0.001639084,0.0005468441],"category_scores_gemma":[0.00009900776,0.0003556758,0.0001691615,0.0003775766,0.0004430163,0.00008576352,0.00007549289,0.002293721,0.0001269146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006509037,"about_ca_system_score_gemma":0.0006985884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001190288,"about_ca_topic_score_gemma":0.0002476803,"domain_scores_codex":[0.9969285,0.0001178663,0.001040808,0.0009903781,0.000373047,0.0005494489],"domain_scores_gemma":[0.9982417,0.0008523085,0.00009056632,0.0003235736,0.0001066245,0.0003851882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002583201,0.001151471,0.009911872,0.001088327,0.02799201,0.02597374,0.002470637,0.000184181,0.004806571,0.02189671,0.8878812,0.01406007],"study_design_scores_gemma":[0.01267973,0.002404859,0.1572904,0.001194381,0.004214973,0.001567229,0.00002520479,0.008081872,0.00003496596,0.0243531,0.7868381,0.001315194],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1422412,0.003184749,0.00007310115,0.8518463,0.0007891173,0.0009792204,0.0001299113,0.0001297519,0.0006266259],"genre_scores_gemma":[0.4578007,0.01721176,0.001379806,0.4804348,0.01415736,0.0003940888,0.003111309,0.0004466865,0.02506346],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.3714114,"threshold_uncertainty_score":0.9998895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04436404195791082,"score_gpt":0.3249015798311541,"score_spread":0.2805375378732433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}