{"id":"W4382912938","doi":"10.1016/j.seizure.2023.07.002","title":"Genetics and SUDEP: Challenges and Future Directions","year":2023,"lang":"en","type":"review","venue":"Seizure","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Epilepsy; Medicine; Pleiotropy; Genetic testing; Polygenic risk score; Autopsy; Neurogenetics; Neuroscience; Bioinformatics; Psychiatry; Phenotype; Genetics; Psychology; Biology; Gene; Pathology; Disease; Genotype; Internal medicine; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008551621,0.000223711,0.0007708536,0.0001349689,0.00007166151,0.00001694802,0.00003660172,0.0002587567,0.00002114073],"category_scores_gemma":[0.00002319905,0.0001490595,0.0001102126,0.000127408,0.00005662667,0.00001226066,0.00006809925,0.0003444947,0.00006191253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003435035,"about_ca_system_score_gemma":0.0001231406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006164905,"about_ca_topic_score_gemma":0.00006460829,"domain_scores_codex":[0.9990953,0.00005586899,0.0001501498,0.000320283,0.0001614229,0.0002170111],"domain_scores_gemma":[0.9993476,0.00009257756,0.00004148975,0.0002524197,0.00003472093,0.0002311428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000284443,0.00003013787,0.00001399374,0.01445315,0.0003640729,0.0002050112,0.0001007533,7.268956e-10,1.758002e-8,0.00009888985,0.0008967405,0.9838344],"study_design_scores_gemma":[0.0002175565,0.0001989567,0.0005403497,0.003668318,0.0007925737,0.0003968795,0.00009045942,4.002382e-7,7.562362e-8,0.00005647899,0.9939302,0.0001077688],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001484238,0.9962317,6.916132e-8,0.001100039,0.0001337705,0.0006410588,0.00006439665,0.00007820485,0.00173592],"genre_scores_gemma":[0.000001397957,0.9956504,0.00007900589,0.00001482315,0.001035164,0.0001050566,0.0001125847,0.00005151275,0.002950074],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9930335,"threshold_uncertainty_score":0.6078469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.121219718385318,"score_gpt":0.401178713005848,"score_spread":0.27995899462053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}