{"id":"W4382912938","doi":"10.1016/j.seizure.2023.07.002","title":"Genetics and SUDEP: Challenges and Future Directions","year":2023,"lang":"en","type":"review","venue":"Seizure","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Epilepsy; Medicine; Pleiotropy; Genetic testing; Polygenic risk score; Autopsy; Neurogenetics; Neuroscience; Bioinformatics; Psychiatry; Phenotype; Genetics; Psychology; Biology; Gene; Pathology; Disease; Genotype; Internal medicine; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001374653,0.0008962294,0.002281763,0.002040463,0.0003047269,0.001832746,0.001098204,0.001869187,0.005966926],"category_scores_gemma":[0.001972213,0.0002682845,0.0006844975,0.002060224,0.0007812246,0.002102628,0.00107002,0.002658501,0.001626371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001082908,"about_ca_system_score_gemma":0.002699846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00221402,"about_ca_topic_score_gemma":0.006421248,"domain_scores_codex":[0.9996965,0.00008607333,0.00004784388,0.00004618906,0.00009089595,0.00003255961],"domain_scores_gemma":[0.9987401,0.0008015937,0.0001195148,0.00002167512,0.0002281094,0.00008895158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001240745,0.00005881956,0.000374849,0.01388657,0.000159018,0.0003794975,0.00005713745,0.0004204645,0.0004269249,0.006553247,0.06625741,0.911302],"study_design_scores_gemma":[0.00005505201,0.00007251676,0.0009964036,0.01300962,0.0003219264,0.001465398,0.00014189,0.0001628403,0.00008666102,0.006420934,0.9772355,0.00003131132],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004119118,0.9979841,0.000074216,0.001158729,0.0002654142,0.000001706941,0.00001467202,0.000005490791,0.00045454],"genre_scores_gemma":[0.0003403613,0.998051,0.0001648151,0.0006915944,0.0004763837,0.00000363136,0.00002286925,0.000001172941,0.0002480397],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005966926,"threshold_uncertainty_score":0.01996136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.121219718385318,"score_gpt":0.401178713005848,"score_spread":0.27995899462053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}