{"id":"W4382930098","doi":"10.1101/2023.07.03.547316","title":"Mechanical Force Imprints Neutrophils to Orchestrate Pulmonary Homeostasis","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"School of Medicine, Shanghai Jiao Tong University; Shanghai Jiao Tong University; National Natural Science Foundation of China","keywords":"PIEZO1; Homeostasis; Mechanosensitive channels; Immune system; Lung; Biology; Cell biology; Immunology; Angiogenesis; Population; Inflammation; Medicine; Cancer research; Internal medicine; Ion channel; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001599013,0.0002013675,0.0001662596,0.0001613484,0.0001298286,0.0003808414,0.0001317244,0.0003209279,0.0008011818],"category_scores_gemma":[0.0001128086,0.0001253147,0.00009559906,0.00006284538,0.0003770321,0.000218378,0.0003499166,0.0005234865,0.0002347613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002248173,"about_ca_system_score_gemma":0.0001204778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002094145,"about_ca_topic_score_gemma":0.000277482,"domain_scores_codex":[0.999864,0.00001689341,0.000006672872,0.0000376814,0.00004173768,0.00003308218],"domain_scores_gemma":[0.9999124,0.00001118659,0.00003325955,0.00001106544,0.000009681259,0.00002248175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000333363,0.000005597886,0.0005942283,0.00001035993,0.00000102219,0.00004172096,0.0000105666,0.00004485043,0.9978823,0.0002564442,0.00004896844,0.001070545],"study_design_scores_gemma":[0.00001578882,0.0001390576,0.03646364,0.00001356558,0.000008482586,0.0004428284,0.00009701143,0.003404522,0.9552109,0.0005416413,0.003653867,0.000008649049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847727,0.001252294,0.01111221,0.000396534,0.00004634281,0.00001987277,0.0002886034,0.0001809475,0.001930428],"genre_scores_gemma":[0.9960486,0.000247745,0.001810212,0.00008679796,0.0000155524,0.00001533129,0.00008665182,0.00001772267,0.001671324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008011818,"threshold_uncertainty_score":0.002680182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03624573875962613,"score_gpt":0.2619804970355997,"score_spread":0.2257347582759736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}