{"id":"W4382930918","doi":"10.1073/pnas.2301115120","title":"Sialic acid plays a pivotal role in licensing <i>Citrobacter rodentium’s</i> transition from the intestinal lumen to a mucosal adherent niche","year":2023,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Crohn's and Colitis Canada; Government of Canada; Canadian Institutes of Health Research; CH.I.L.D. Foundation; Macquarie University; BC Children's Hospital","keywords":"Citrobacter rodentium; Niche; Lumen (anatomy); Sialic acid; Microbiology; Citrobacter; Chemistry; Cell biology; Biology; Enterobacteriaceae; Biochemistry; Escherichia coli; Pathogen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001503605,0.0005316728,0.0002296277,0.0001702786,0.0002384087,0.0006129421,0.0002582636,0.0004295017,0.001134088],"category_scores_gemma":[0.0001774638,0.0001587809,0.0003907838,0.0001526786,0.0003015751,0.0004828108,0.0005761056,0.0004321058,0.0004026353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002581356,"about_ca_system_score_gemma":0.0003158356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001341251,"about_ca_topic_score_gemma":0.001154891,"domain_scores_codex":[0.9998372,0.00002187656,0.00001498038,0.0000281479,0.00003905822,0.0000586769],"domain_scores_gemma":[0.9998792,0.000007484503,0.00003332691,0.00001451134,0.00002511574,0.00004018577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001150674,0.00002273015,0.002647306,0.00009428935,0.000008688972,0.0001992201,0.00003863285,0.00007747085,0.9930035,0.0003054372,0.0001038204,0.003383825],"study_design_scores_gemma":[0.00002215126,0.000507821,0.04390635,0.00006000603,0.00004735401,0.001288181,0.0004439765,0.00155939,0.939148,0.0004381717,0.01254065,0.00003793563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809974,0.00467828,0.004435649,0.0005799357,0.0001005098,0.00005698314,0.0003866028,0.0001274875,0.008637162],"genre_scores_gemma":[0.9951415,0.0009934809,0.00212884,0.0001493185,0.00001213147,0.00001086093,0.0002889363,0.0000167078,0.001258172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001341251,"threshold_uncertainty_score":0.003793955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03430065548988991,"score_gpt":0.2577772646208479,"score_spread":0.223476609130958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}