{"id":"W4382932491","doi":"10.1530/ec-22-0440","title":"Sex chromosome aneuploidies and fertility: 47,XXY, 47,XYY, 47,XXX and 45,X/47,XXX","year":2023,"lang":"en","type":"review","venue":"Endocrine Connections","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"World Anti-Doping Agency","keywords":"Klinefelter syndrome; Karyotype; Testicular sperm extraction; Azoospermia; Population; Infertility; Male infertility; Fertility; Turner syndrome; Gynecology; Medicine; Biology; Chromosome; Genetics; Endocrinology; Pregnancy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002170989,0.0007083272,0.001331711,0.0001831832,0.0004692541,0.0001515948,0.0002939914,0.00039111,0.0002107711],"category_scores_gemma":[0.0003896109,0.0006308493,0.0004252494,0.0002671333,0.0004485604,0.00001040866,0.0005764235,0.0004667203,0.00009636038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003112427,"about_ca_system_score_gemma":0.0001765709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007581503,"about_ca_topic_score_gemma":0.0002014463,"domain_scores_codex":[0.9968923,0.0002156108,0.0009390442,0.001105583,0.0002415539,0.0006058862],"domain_scores_gemma":[0.9983816,0.00025908,0.0002942529,0.000581009,0.00014458,0.0003394452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001002669,0.0007766418,0.0005915979,0.02022034,0.002630083,0.0003619105,0.0003364994,0.000007496373,0.001067296,0.001860408,0.01555644,0.9564911],"study_design_scores_gemma":[0.0005845982,0.0005564459,0.0002834288,0.0008035823,0.0005327625,0.0005800084,0.0004404386,0.00001465167,0.0005499938,0.0004075973,0.9944428,0.0008036544],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03408381,0.9610814,0.00001942874,0.0004854988,0.0006716281,0.000783083,0.0004088199,0.0001782742,0.002288011],"genre_scores_gemma":[0.01947313,0.9510497,0.00006906479,0.0002095517,0.000804243,0.0002914237,0.0004670592,0.0001083773,0.02752738],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9788864,"threshold_uncertainty_score":0.9996143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04619942201230171,"score_gpt":0.3356477389850062,"score_spread":0.2894483169727045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}