{"id":"W4382932491","doi":"10.1530/ec-22-0440","title":"Sex chromosome aneuploidies and fertility: 47,XXY, 47,XYY, 47,XXX and 45,X/47,XXX","year":2023,"lang":"en","type":"review","venue":"Endocrine Connections","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"World Anti-Doping Agency","keywords":"Klinefelter syndrome; Karyotype; Testicular sperm extraction; Azoospermia; Population; Infertility; Male infertility; Fertility; Turner syndrome; Gynecology; Medicine; Biology; Chromosome; Genetics; Endocrinology; Pregnancy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004709784,0.0005499586,0.0004779142,0.00192157,0.0002595947,0.00078929,0.000496421,0.001022602,0.003861257],"category_scores_gemma":[0.001050988,0.0001326729,0.0002933429,0.001333285,0.0007105451,0.0007880807,0.0006623561,0.0008750461,0.001072512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003391365,"about_ca_system_score_gemma":0.0004905835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00134102,"about_ca_topic_score_gemma":0.001483605,"domain_scores_codex":[0.99972,0.00007044018,0.00003846141,0.00002838467,0.0001012902,0.00004128598],"domain_scores_gemma":[0.9995802,0.0001925394,0.0001135476,0.000007180159,0.00005812488,0.00004831883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002631081,0.0001223753,0.02376097,0.004731962,0.000224739,0.006881265,0.0007710753,0.000549142,0.005731585,0.01337613,0.1250604,0.8185273],"study_design_scores_gemma":[0.0000192463,0.0005568116,0.06287999,0.002764336,0.00009914712,0.05734634,0.0008179973,0.0001549815,0.001292145,0.006877444,0.8671386,0.00005307119],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004959176,0.9849346,0.0004207361,0.002837729,0.001037566,0.00001902189,0.0000786572,0.00001984894,0.005692714],"genre_scores_gemma":[0.03619947,0.9453583,0.0006488964,0.002018987,0.003984431,0.000041544,0.0003186546,0.00001417248,0.0114155],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003861257,"threshold_uncertainty_score":0.01291716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04619942201230171,"score_gpt":0.3356477389850062,"score_spread":0.2894483169727045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}