{"id":"W4382937076","doi":"10.1038/s41592-023-01915-x","title":"Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions","year":2023,"lang":"en","type":"review","venue":"Nature Methods","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of General Medical Sciences; Fondazione Cassa di Risparmio di Firenze; Horizon 2020 Framework Programme; Vrije Universiteit Brussel; Fondazione Umberto Veronesi; Danmarks Grundforskningsfond; European Commission; National Research, Development and Innovation Office; National Institutes of Health; Cancer Research UK","keywords":"Intrinsically disordered proteins; Computational biology; Computer science; Biology; Nanotechnology; Biophysics; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.01129286,0.003371791,0.003506026,0.006275547,0.001102347,0.002010579,0.006935734,0.006374549,0.01048035],"category_scores_gemma":[0.01353251,0.002038716,0.001893111,0.004051366,0.00231494,0.003250529,0.003356342,0.005470541,0.01243753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002048153,"about_ca_system_score_gemma":0.005965351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002837524,"about_ca_topic_score_gemma":0.0040079,"domain_scores_codex":[0.9933525,0.001748523,0.001249311,0.0005021179,0.002807369,0.0003400776],"domain_scores_gemma":[0.9859617,0.007928619,0.001052511,0.001475948,0.003225674,0.0003554846],"domain_codex":null,"domain_gemma":"reporting","domain_candidate":"reporting","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003899463,0.0002897232,0.0002943909,0.02821134,0.0001134786,0.0004426958,0.000192705,0.001397542,0.02507749,0.04434193,0.1796992,0.7195494],"study_design_scores_gemma":[0.00011541,0.0001544536,0.0007660948,0.008517167,0.0001641532,0.0009135199,0.00006206528,0.0008154753,0.02154042,0.02819631,0.938666,0.00008898592],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.001650001,0.6395177,0.2841609,0.01157412,0.005051265,0.002011449,0.008558437,0.005776207,0.04170007],"genre_scores_gemma":[0.007110903,0.4627129,0.4728759,0.009359084,0.001554739,0.006285837,0.01918849,0.001159261,0.01975302],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.9887071,"threshold_uncertainty_score":0.05972308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0897866523454103,"score_gpt":0.4735437808190353,"score_spread":0.383757128473625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}