{"id":"W4382982334","doi":"10.3390/polym15132919","title":"Injectable Lyophilized Chitosan-Thrombin-Platelet-Rich Plasma (CS-FIIa-PRP) Implant to Promote Tissue Regeneration: In Vitro and Ex Vivo Solidification Properties","year":2023,"lang":"en","type":"article","venue":"Polymers","topic":"Tendon Structure and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Biomaterial; Ex vivo; Biomedical engineering; Thromboelastography; Chitosan; Platelet-rich plasma; Thrombin; Tissue engineering; Regeneration (biology); Materials science; Platelet; In vivo; Chemistry; In vitro; Medicine; Biochemistry; Immunology; Biotechnology; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007522349,0.0002219025,0.0003627641,0.0002686699,0.0001074713,0.00004176606,0.00006358239,0.00009570441,0.0000461247],"category_scores_gemma":[0.00003018607,0.0001731565,0.00003134929,0.0005067161,0.00004169248,0.00009784508,0.00004724234,0.0001076088,0.00007667728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006084139,"about_ca_system_score_gemma":0.00008495943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003706872,"about_ca_topic_score_gemma":0.00005756633,"domain_scores_codex":[0.9986269,0.00003722156,0.0002987126,0.0004143847,0.0002384898,0.00038429],"domain_scores_gemma":[0.9994388,0.00001919079,0.00006164541,0.0002839204,0.00002378253,0.0001727073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004563795,0.00005624288,0.0001999976,0.00007473982,0.00006491361,0.0001026015,0.002366334,0.00001534809,0.9716361,0.00003479809,0.0005464363,0.02444606],"study_design_scores_gemma":[0.002144334,0.0003217578,0.002938934,0.00005315238,0.00005346252,0.0003565417,0.0003097975,0.0001562152,0.9905722,0.00002979711,0.002885385,0.0001784497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932513,0.0007286302,0.000006656374,0.00357226,0.0003336263,0.0009758717,0.00003038144,0.0001548588,0.0009463769],"genre_scores_gemma":[0.996536,0.0002154025,0.0003197969,0.0002152216,0.0001417782,0.0001418615,0.0001308112,0.00003526525,0.002263837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02426761,"threshold_uncertainty_score":0.7061117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02213611914425304,"score_gpt":0.2688603916596458,"score_spread":0.2467242725153927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}