{"id":"W4383059223","doi":"10.1002/cncr.34910","title":"Enzalutamide shows sustained overall survival improvement in patients with metastatic hormone‐sensitive prostate cancer","year":2023,"lang":"en","type":"article","venue":"Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Enzalutamide; Medicine; Prostate cancer; Bicalutamide; Flutamide; Oncology; Antiandrogen; Testosterone (patch); Docetaxel; Internal medicine; Cancer; Interim analysis; Randomized controlled trial; Gynecology; Androgen receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006091009,0.0003869466,0.001075251,0.0001921146,0.0001520032,0.0003577716,0.0002866428,0.0002689445,0.001535808],"category_scores_gemma":[0.0005403499,0.0002077099,0.0009474412,0.0003037879,0.0002867849,0.0002477808,0.0001494162,0.0008262344,0.0001750218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003793193,"about_ca_system_score_gemma":0.0004570688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001440411,"about_ca_topic_score_gemma":0.005915242,"domain_scores_codex":[0.9998011,0.00009718501,0.00001289396,0.00002700535,0.00002672101,0.00003513181],"domain_scores_gemma":[0.9997695,0.00004787367,0.00005954401,0.00001778574,0.0000165827,0.00008872708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.7170247,0.008141676,0.02273714,0.001252785,0.00306902,0.0004052048,0.0001486496,0.002267244,0.03497144,0.0001540866,0.004993254,0.2048349],"study_design_scores_gemma":[0.3380511,0.4217357,0.2199483,0.0001528663,0.002568154,0.0009641548,0.0001050223,0.002297974,0.006020502,0.0004963399,0.007578366,0.00008166371],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99058,0.007072408,0.0001189755,0.0003095546,0.0001190038,0.0001091757,0.0002594642,0.00003887566,0.001392453],"genre_scores_gemma":[0.9958807,0.002226156,0.0002004613,0.0003298876,0.00006761627,0.00005635548,0.0004736895,0.00000467155,0.0007603823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001535808,"threshold_uncertainty_score":0.005137801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02087839201243595,"score_gpt":0.3122442329283145,"score_spread":0.2913658409158785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}