{"id":"W4383102025","doi":"10.1016/j.ibneur.2023.06.007","title":"Beneficial immune-modulatory effects of the N-163 strain of Aureobasidium pullulans-produced 1,3-1,6 Beta glucans in Duchenne muscular dystrophy: Results of an open-label, prospective, exploratory case-control clinical study","year":2023,"lang":"en","type":"article","venue":"IBRO Neuroscience Reports","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thunder Bay Regional Health Sciences Centre","funders":"","keywords":"Duchenne muscular dystrophy; Medicine; Aureobasidium pullulans; Internal medicine; Muscular dystrophy; Gastroenterology; Endocrinology; Biology; Food science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005901322,0.0003500836,0.0005550496,0.0002002138,0.0002253777,0.000201687,0.0001902732,0.0004168079,0.0006763245],"category_scores_gemma":[0.0004413794,0.0001149498,0.0002985143,0.0001142609,0.0003748058,0.0001693221,0.000117751,0.000231806,0.0001000901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001740964,"about_ca_system_score_gemma":0.0001610561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002024583,"about_ca_topic_score_gemma":0.000318894,"domain_scores_codex":[0.9997806,0.00008537275,0.00002147336,0.00004363962,0.00004528015,0.00002369906],"domain_scores_gemma":[0.9996904,0.00007776097,0.0001013234,0.00002294203,0.00002411357,0.00008359004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1554797,0.04104498,0.3892863,0.001053785,0.0006492884,0.008138457,0.0005216183,0.0004884129,0.3207241,0.0001086973,0.0003523391,0.08215239],"study_design_scores_gemma":[0.006165336,0.3442336,0.6179527,0.00006280899,0.000400339,0.01007783,0.0003157536,0.0005755586,0.01899403,0.0000500375,0.00114609,0.00002597794],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995515,0.000296127,0.00003438538,0.000006133349,0.000002529059,0.00002232198,0.00001114572,0.000001345128,0.00007457541],"genre_scores_gemma":[0.9996346,0.0001454226,0.00007908619,0.00001877519,0.00001046659,0.00001582982,0.00002814819,5.837442e-7,0.00006698689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006763245,"threshold_uncertainty_score":0.003120959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02846978096499085,"score_gpt":0.3238536226867907,"score_spread":0.2953838417217999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}