{"id":"W4383187106","doi":"10.1111/febs.16873","title":"Role of developmental pathways in disease","year":2023,"lang":"en","type":"editorial","venue":"FEBS Journal","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Epigenetics; Biology; Disease; Signal transduction; Neuroscience; Epigenesis; Human disease; Computational biology; Genetics; DNA methylation; Gene; Gene expression; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003946799,0.002772062,0.002712171,0.002229123,0.001511993,0.004542333,0.00215048,0.007013266,0.008720188],"category_scores_gemma":[0.007124073,0.0006785092,0.001448254,0.0009130434,0.00220619,0.003179086,0.001700145,0.0123017,0.00578233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002447563,"about_ca_system_score_gemma":0.001848268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006035299,"about_ca_topic_score_gemma":0.001417276,"domain_scores_codex":[0.9982827,0.0003337604,0.0002530697,0.0002856923,0.000710523,0.0001342407],"domain_scores_gemma":[0.9942932,0.002610474,0.0003301024,0.0001598624,0.001585333,0.001020991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009565465,0.00001571054,0.00004293308,0.0007175615,0.00003070734,0.0002854887,0.00003227222,0.00004832181,0.0003303072,0.00170349,0.9701962,0.02650137],"study_design_scores_gemma":[0.00003439461,0.00003988502,0.0001899604,0.0004369223,0.00003263204,0.0005265921,0.00002988926,0.00008244963,0.0001275128,0.001562755,0.9969257,0.00001132313],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.00007248338,0.0624357,0.0001997787,0.02772126,0.9078684,0.00001367102,0.00003624261,0.00006132688,0.001591075],"genre_scores_gemma":[0.0006249824,0.050129,0.0001622626,0.0133813,0.9286007,0.00001495055,0.00002797043,0.00002979682,0.007029062],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.008720188,"threshold_uncertainty_score":0.02917194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0101736973485786,"score_gpt":0.2523917446204153,"score_spread":0.2422180472718367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}