{"id":"W4383187124","doi":"10.1093/brain/awad223","title":"A cholinergic contribution to postural control and freezing of gait in Parkinson’s disease","year":2023,"lang":"en","type":"letter","venue":"Brain","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Newcastle upon Tyne Hospitals NHS Foundation Trust; Newcastle University; Dunhill Medical Trust; Weston Brain Institute; Parkinson's UK; National Institute for Health and Care Research; Michael J. Fox Foundation for Parkinson's Research; Lewy Body Society","keywords":"Parkinson's disease; Physical medicine and rehabilitation; Cholinergic; Gait; Disease; Neuroscience; Psychology; Medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002043932,0.0007633771,0.001934927,0.0007174949,0.002391365,0.001791718,0.001814951,0.03641872,0.003882667],"category_scores_gemma":[0.01306545,0.000503401,0.001100491,0.0008208065,0.002204166,0.002618117,0.0008993364,0.02461996,0.004971525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002454316,"about_ca_system_score_gemma":0.002188691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005861264,"about_ca_topic_score_gemma":0.008543636,"domain_scores_codex":[0.9984148,0.00037948,0.0003038731,0.0002644818,0.0004533031,0.0001840866],"domain_scores_gemma":[0.9926789,0.004839658,0.000398844,0.0001902833,0.001436408,0.0004560207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0001791786,0.00003341078,0.000475964,0.0001804725,0.00002241408,0.003255129,0.0001032628,0.00003633279,0.0002670267,0.001069469,0.9800684,0.0143089],"study_design_scores_gemma":[0.0007265944,0.0003809992,0.006621254,0.001507596,0.0001680533,0.01437802,0.0005083561,0.0008821849,0.0008072006,0.01818888,0.9556642,0.0001667256],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.0006904507,0.007828678,0.0001025947,0.9451209,0.04400631,0.00001047771,0.00009083842,0.00003211309,0.002117548],"genre_scores_gemma":[0.008574836,0.00748654,0.0001947946,0.6859084,0.292742,0.00004073542,0.00006422739,0.00002629815,0.004962166],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03641872,"threshold_uncertainty_score":0.01780736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01377440893799936,"score_gpt":0.264763568990707,"score_spread":0.2509891600527076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}