{"id":"W4383198753","doi":"10.3389/fendo.2023.1202560","title":"Protective effects of melatonin against oxidative stress induced by metabolic disorders in the male reproductive system: a systematic review and meta-analysis of rodent models","year":2023,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Internal medicine; Endocrinology; Melatonin; Male infertility; Oxidative stress; Medicine; Infertility; Metabolic syndrome; Leptin; Diabetes mellitus; Polycystic ovary; Obesity; Biology; Insulin resistance; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006437368,0.001818949,0.01138157,0.00615391,0.0005072581,0.001960857,0.001704429,0.001358528,0.002513348],"category_scores_gemma":[0.0151336,0.0008817565,0.01817426,0.006350071,0.0005177492,0.001006069,0.001002336,0.0008942044,0.0001752782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001351937,"about_ca_system_score_gemma":0.00297848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004521743,"about_ca_topic_score_gemma":0.01191378,"domain_scores_codex":[0.996334,0.001342115,0.001346798,0.0004275192,0.0004244378,0.0001251083],"domain_scores_gemma":[0.9876036,0.008352735,0.002567929,0.0003629268,0.0009362398,0.0001766532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001521867,0.0000473114,0.006254531,0.6657004,0.2989108,0.0001554891,0.0001074486,0.0003609316,0.0004291176,0.0001288522,0.0007427493,0.02564066],"study_design_scores_gemma":[0.0004232864,0.0003435405,0.01009069,0.0512589,0.9334522,0.0001970938,0.00007628471,0.0001303206,0.0001984427,0.0001886163,0.003608616,0.00003209672],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004012354,0.9948488,0.0002396768,0.000119749,0.00005919294,0.0001257382,0.0004445103,0.00001135744,0.0001386726],"genre_scores_gemma":[0.09255992,0.9044594,0.001106513,0.0005000806,0.000152975,0.0003862003,0.0006773331,0.00001353966,0.0001439407],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01138157,"threshold_uncertainty_score":0.03404444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0427418010248335,"score_gpt":0.3060126467974725,"score_spread":0.263270845772639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}