{"id":"W4383216565","doi":"10.1016/j.actbio.2023.06.045","title":"An in vitro autologous, vascularized, and immunocompetent Tissue Engineered Skin model obtained by the self-assembled approach","year":2023,"lang":"en","type":"article","venue":"Acta Biomaterialia","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Fonds de Recherche du Québec - Santé; Mitacs","keywords":"Dermis; Immune system; Flow cytometry; In vitro; Cell type; Immunology; Cell; Epidermis (zoology); Tissue engineering; Skin equivalent; Cell biology; Biology; Pathology; Medicine; Keratinocyte; Biomedical engineering; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001996488,0.0003364564,0.0001745755,0.0002658673,0.0001741967,0.0002610576,0.0002843439,0.0003193731,0.0007571388],"category_scores_gemma":[0.00008506626,0.0001888704,0.0002779849,0.000114018,0.0001550856,0.0002213892,0.0001913654,0.0005555201,0.0003171318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001181011,"about_ca_system_score_gemma":0.0002133519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002981105,"about_ca_topic_score_gemma":0.0007243369,"domain_scores_codex":[0.9998817,0.00001421074,0.000008946598,0.00003370575,0.00003949145,0.0000219498],"domain_scores_gemma":[0.9998897,0.00002467858,0.00002574522,0.00002210179,0.00001295891,0.00002478542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002033151,0.00001465527,0.00002968832,0.00001417446,0.000001617822,0.00007858341,0.0000068462,0.00005153444,0.9994159,0.0001117881,0.00001001524,0.0002448103],"study_design_scores_gemma":[0.000005870512,0.0001822089,0.001352264,0.000004363127,0.00001653472,0.0004546062,0.00002042934,0.001335592,0.9951518,0.00006166251,0.00140966,0.000005060698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.958406,0.0009184604,0.03465437,0.00009094276,0.0001409807,0.0001119687,0.0006279061,0.0002323696,0.004816987],"genre_scores_gemma":[0.9674549,0.0004873451,0.02540755,0.00008889733,0.00001563816,0.0001107645,0.0004407257,0.00004053569,0.005953621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007571388,"threshold_uncertainty_score":0.00253284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008615083943709322,"score_gpt":0.2255474132824692,"score_spread":0.2169323293387598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}