{"id":"W4383293155","doi":"10.1093/bjd/ljad220","title":"Boost of innate immunity cytokines as biomarkers of response to extracorporeal photopheresis in patients with leukaemic cutaneous T-cell lymphoma","year":2023,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Cutaneous lymphoproliferative disorders research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"European Academy of Dermatology and Venereology; Sun Pharma; EMBO; National Institutes of Health; Helsinn; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Universität Zürich; Narodowe Centrum Nauki; Swiss Cancer Research Foundation; European Commission; National Science Foundation; Les Laboratories Pierre Fabre; Promedica Stiftung; Cancer Research Foundation; Bristol-Myers Squibb","keywords":"Medicine; Extracorporeal Photopheresis; Cutaneous T-cell lymphoma; Immunology; Photopheresis; Peripheral blood mononuclear cell; Cytokine; Tumor necrosis factor alpha; Immune system; Lymphoma; Internal medicine; Mycosis fungoides; Graft-versus-host disease; Transplantation; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003911623,0.000184066,0.0008826352,0.0009975336,0.00005317537,0.000014267,0.0002961791,0.0001604664,0.00008834404],"category_scores_gemma":[0.001110856,0.0001881267,0.0001388392,0.001144156,0.0003153338,0.00008570522,0.0001047949,0.0002394488,0.0000135498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001634092,"about_ca_system_score_gemma":0.0008494728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000956027,"about_ca_topic_score_gemma":0.0003127878,"domain_scores_codex":[0.9971366,0.0005313996,0.001049558,0.0002042184,0.000649806,0.0004284356],"domain_scores_gemma":[0.9976444,0.0005105671,0.0005158033,0.000244939,0.0008680971,0.0002161573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.07629167,0.001931327,0.7865906,0.0003917039,0.0003657172,0.04414406,0.0008149497,0.00003829551,0.07401033,0.000002945168,0.002412515,0.01300582],"study_design_scores_gemma":[0.01939612,0.003123024,0.7350389,0.001183246,0.00009022856,0.1702094,0.001271334,0.00005608869,0.06908525,0.00008333905,0.0002013649,0.0002616507],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980708,0.000408767,0.000006584082,0.0004026453,0.00006034526,0.0004911002,0.00006439342,0.00001355189,0.0004817802],"genre_scores_gemma":[0.9991978,0.0003001369,0.0002211619,0.00009769505,0.00000892958,0.000007675525,0.00002083782,0.000040905,0.0001048588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1260653,"threshold_uncertainty_score":0.7671583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008715627945288308,"score_gpt":0.2617786532048653,"score_spread":0.253063025259577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}