{"id":"W4383293155","doi":"10.1093/bjd/ljad220","title":"Boost of innate immunity cytokines as biomarkers of response to extracorporeal photopheresis in patients with leukaemic cutaneous T-cell lymphoma","year":2023,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Cutaneous lymphoproliferative disorders research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"European Academy of Dermatology and Venereology; Sun Pharma; EMBO; National Institutes of Health; Helsinn; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Universität Zürich; Narodowe Centrum Nauki; Swiss Cancer Research Foundation; European Commission; National Science Foundation; Les Laboratories Pierre Fabre; Promedica Stiftung; Cancer Research Foundation; Bristol-Myers Squibb","keywords":"Medicine; Extracorporeal Photopheresis; Cutaneous T-cell lymphoma; Immunology; Photopheresis; Peripheral blood mononuclear cell; Cytokine; Tumor necrosis factor alpha; Immune system; Lymphoma; Internal medicine; Mycosis fungoides; Graft-versus-host disease; Transplantation; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003559829,0.0002326649,0.0003255817,0.0004357321,0.0002185304,0.000426253,0.0001720896,0.0003012263,0.0008552338],"category_scores_gemma":[0.000924198,0.0001153371,0.0001792924,0.00038255,0.0001588586,0.00026092,0.0001803816,0.0003671777,0.0001543746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001839953,"about_ca_system_score_gemma":0.0001327362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002644606,"about_ca_topic_score_gemma":0.0002867389,"domain_scores_codex":[0.9997765,0.00005389903,0.00003465847,0.00006418994,0.00003723112,0.00003346015],"domain_scores_gemma":[0.9994187,0.0001276042,0.0002689943,0.0000330406,0.00006631013,0.00008530498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009048776,0.00006837197,0.9908677,0.00003025101,0.00002447121,0.0003521199,0.00007570643,0.00005921391,0.004018205,0.00001156033,0.00006666907,0.003520812],"study_design_scores_gemma":[0.00004445003,0.0009215834,0.9938316,0.00001281919,0.00006989991,0.002624662,0.0001622705,0.0003566464,0.001541808,0.0000308283,0.0003982194,0.000005115032],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990828,0.0004943953,0.0000949774,0.00001715914,0.000003536152,0.00001326129,0.00009341988,0.000004152507,0.0001962733],"genre_scores_gemma":[0.9996436,0.0000667819,0.0000866461,0.0000177958,0.000007943768,0.000011211,0.0001027053,7.231313e-7,0.00006261207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008552338,"threshold_uncertainty_score":0.002861083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008715627945288308,"score_gpt":0.2617786532048653,"score_spread":0.253063025259577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}