{"id":"W4383315117","doi":"10.1101/2023.07.05.547852","title":"pUdOs: concise plasmids for bacterial and mammalian cells","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Government of Ontario; University of Ottawa","keywords":"Plasmid; Biology; Escherichia coli; Promoter; Expression vector; Genetics; Vector (molecular biology); Cloning vector; Multiple cloning site; Transcription (linguistics); Computational biology; Gene; Gene expression; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002438713,0.001981222,0.001990025,0.002757091,0.001937502,0.002035629,0.003485736,0.001452553,0.02656929],"category_scores_gemma":[0.002307386,0.002747651,0.00108805,0.002763301,0.001039678,0.001138015,0.002373625,0.004444525,0.04785159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008357383,"about_ca_system_score_gemma":0.00118232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00058307,"about_ca_topic_score_gemma":0.001386746,"domain_scores_codex":[0.9973897,0.0005338308,0.00044429,0.0004103619,0.0009258908,0.0002959254],"domain_scores_gemma":[0.9988607,0.0003207404,0.0001289602,0.0003579338,0.0001645392,0.0001671549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001205885,0.0004895711,0.0004942826,0.002704151,0.0001104467,0.001052421,0.0009280244,0.001890689,0.7391708,0.03167003,0.1183152,0.1019686],"study_design_scores_gemma":[0.0003731083,0.0002506749,0.0006520256,0.0002018454,0.00005011032,0.0009601231,0.00006133493,0.001696855,0.2790551,0.003628574,0.7129657,0.0001044439],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.02710879,0.006163524,0.7650273,0.001145416,0.001839107,0.00686529,0.1279155,0.03951191,0.02442317],"genre_scores_gemma":[0.07629782,0.007204191,0.4926023,0.0006555464,0.0004069559,0.0158537,0.3182729,0.01324018,0.07546647],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.02656929,"threshold_uncertainty_score":0.08888316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01193913943960876,"score_gpt":0.2479462321851803,"score_spread":0.2360070927455716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}