{"id":"W4383554928","doi":"10.1016/j.celrep.2023.112781","title":"Structure and assembly of type VI secretion system cargo delivery vehicle","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"China Postdoctoral Science Foundation; Natural Science Foundation of Shaanxi Province; National Natural Science Foundation of China; Lanzhou University","keywords":"Trimer; Type VI secretion system; Random hexamer; Chemistry; Biophysics; Secretion; Effector; Cell biology; Nanotechnology; Crystallography; Materials science; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001182317,0.00007185988,0.000106921,0.00003101815,0.00004335677,0.00001034916,0.00003559696,0.00007947523,0.000003846782],"category_scores_gemma":[0.00005789999,0.00006471435,0.00002623556,0.00009711351,0.00003880492,0.000002377796,0.0001356821,0.00003791836,0.000002043789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001053913,"about_ca_system_score_gemma":0.00005001442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002970557,"about_ca_topic_score_gemma":0.000008689746,"domain_scores_codex":[0.9993662,0.00002755865,0.0001478674,0.0002072061,0.0001134154,0.0001377243],"domain_scores_gemma":[0.9995272,0.00000655838,0.00008455882,0.0002155616,0.0001226701,0.0000434362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001874022,0.000003731908,0.007665069,0.0001433131,0.00002165554,0.00008062482,0.00003014513,0.00001601112,0.9906878,0.000001883428,0.001092392,0.0002386307],"study_design_scores_gemma":[0.0001204062,0.0001524302,0.03312377,0.00002639837,0.00001352122,0.00005680795,0.0001765052,0.0001383355,0.9634493,0.000008589627,0.002643118,0.00009083662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998302,0.0007086264,0.000006255742,0.00001289568,0.0001697531,0.0001047282,0.000009758521,0.00001779924,0.0006681735],"genre_scores_gemma":[0.999063,0.0002656269,0.00003470274,0.000005849435,0.0000734269,0.000003392131,0.00009287299,0.00001109344,0.0004499999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02723852,"threshold_uncertainty_score":0.2638974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009224650483560776,"score_gpt":0.2423524306673847,"score_spread":0.233127780183824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}