{"id":"W4383597913","doi":"10.3389/fimmu.2023.1089664","title":"Five-year follow-up of a phase I trial of donor-derived modified immune cell infusion in kidney transplantation","year":2023,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bundesministerium für Bildung und Forschung; Universitätsklinikum Heidelberg; University of Alberta","keywords":"Immunosuppression; Medicine; Transplantation; Kidney transplantation; Internal medicine; Clinical trial; Lymphocyte; Immune system; CD19; Surgery; Urology; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00438184,0.0005943683,0.001350987,0.000377542,0.0005160172,0.001168563,0.0003599473,0.0008450469,0.0008908411],"category_scores_gemma":[0.003624791,0.000199473,0.0009146921,0.0003267799,0.00046649,0.0006773894,0.0005149547,0.001060603,0.0002105409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005150072,"about_ca_system_score_gemma":0.000514088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003896798,"about_ca_topic_score_gemma":0.0003633286,"domain_scores_codex":[0.9981987,0.0007386071,0.0002013325,0.0001819047,0.0002287049,0.0004507344],"domain_scores_gemma":[0.996758,0.0006365072,0.0009077266,0.0002817299,0.0002747838,0.001141235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2395473,0.03451704,0.5022452,0.0006789782,0.004260816,0.002246124,0.0007551606,0.00376323,0.02517326,0.000506358,0.004022454,0.1822841],"study_design_scores_gemma":[0.01941309,0.5294046,0.4364378,0.00007331922,0.001817092,0.001561674,0.0002194585,0.001989172,0.005287126,0.0003493957,0.003396586,0.00005069219],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953815,0.002369096,0.0005293748,0.0001576061,0.00006515493,0.0002732589,0.0002473645,0.00001991477,0.0009567724],"genre_scores_gemma":[0.998096,0.0002476108,0.0001496591,0.0003664431,0.0000563837,0.00009940255,0.0006798958,0.00000310237,0.0003014575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00438184,"threshold_uncertainty_score":0.02317363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01747764067838551,"score_gpt":0.2814698081115125,"score_spread":0.2639921674331269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}