{"id":"W4383621603","doi":"10.1002/hipo.23568","title":"A complex relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin","year":2023,"lang":"en","type":"article","venue":"Hippocampus","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Mental Health; National Institutes of Health; Université Paris-Sud; Fondation Pierre Deniker pour la Recherche et la Prévention en Santé Mentale; Université Paris-Saclay; University of Toronto; National Alliance for Research on Schizophrenia and Depression","keywords":"Doublecortin; Neurogenesis; Hippocampal formation; Fluoxetine; Downregulation and upregulation; Neuroscience; Gene knockdown; Antidepressant; Progenitor cell; Biology; Hippocampus; Cell biology; Dentate gyrus; Internal medicine; Stem cell; Serotonin; Medicine; Cell culture; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001804778,0.0002481993,0.0003615234,0.0001707616,0.0002165044,0.00002610583,0.0003958563,0.0001230751,0.00004449677],"category_scores_gemma":[0.0007377024,0.0001868354,0.0001469597,0.000903252,0.0001865826,0.000129322,0.0003587672,0.0002252234,0.00001738891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008891306,"about_ca_system_score_gemma":0.00003805531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005063342,"about_ca_topic_score_gemma":0.000001938917,"domain_scores_codex":[0.9974309,0.0005103726,0.0005718999,0.0005684117,0.0005745424,0.0003438517],"domain_scores_gemma":[0.9980458,0.0007781826,0.0004768223,0.0005153687,0.00007861327,0.0001051837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001079987,0.00003237631,0.00996035,0.00008444428,0.000003068194,0.00001126937,0.0001069406,0.00005749222,0.9872655,0.0003881664,0.0001518229,0.00183055],"study_design_scores_gemma":[0.0003474891,0.00008331233,0.3738898,0.00004585946,0.00002472952,0.00001748385,0.00001197257,0.0003961829,0.6244867,0.0005330115,0.0000645212,0.00009894874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985054,0.00001245143,0.00007308738,0.0002048954,0.0004157598,0.0004123439,0.0001295929,0.000101599,0.00014487],"genre_scores_gemma":[0.999377,0.0000515434,0.00006656651,0.0002909622,0.00005263513,0.00001314245,0.000003498434,0.00005115896,0.00009349427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3639294,"threshold_uncertainty_score":0.7618927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05076298688994845,"score_gpt":0.2677628770819094,"score_spread":0.216999890191961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}