{"id":"W4383621603","doi":"10.1002/hipo.23568","title":"A complex relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin","year":2023,"lang":"en","type":"article","venue":"Hippocampus","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Mental Health; National Institutes of Health; Université Paris-Sud; Fondation Pierre Deniker pour la Recherche et la Prévention en Santé Mentale; Université Paris-Saclay; University of Toronto; National Alliance for Research on Schizophrenia and Depression","keywords":"Doublecortin; Neurogenesis; Hippocampal formation; Fluoxetine; Downregulation and upregulation; Neuroscience; Gene knockdown; Antidepressant; Progenitor cell; Biology; Hippocampus; Cell biology; Dentate gyrus; Internal medicine; Stem cell; Serotonin; Medicine; Cell culture; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001880838,0.0002776604,0.0003064919,0.0003902051,0.0001310602,0.0003388554,0.0001656878,0.0002632044,0.0007536939],"category_scores_gemma":[0.0001511743,0.0001822712,0.0001044627,0.0002087475,0.0004204778,0.0003538432,0.0002166306,0.0006177641,0.000150436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002411249,"about_ca_system_score_gemma":0.0002069165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006565277,"about_ca_topic_score_gemma":0.001697243,"domain_scores_codex":[0.9998052,0.00001240596,0.00002037626,0.00006561991,0.00006945944,0.00002699071],"domain_scores_gemma":[0.999796,0.00003729805,0.0000730599,0.00002318076,0.00003729663,0.00003320694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004501416,0.000008730979,0.000776779,0.0000246754,0.000004784762,0.0000322692,0.00001672789,0.00001071856,0.9978157,0.00005087068,0.000009711108,0.001203966],"study_design_scores_gemma":[0.00001312696,0.0003790485,0.1031205,0.00001875375,0.00004026411,0.0004791868,0.0000922599,0.0003455646,0.8935506,0.0002716841,0.001678879,0.00001022625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847269,0.004342084,0.007934106,0.0001198469,0.00002961494,0.00004159269,0.0004843413,0.00007685878,0.00224471],"genre_scores_gemma":[0.9866083,0.001891519,0.00838393,0.0001317949,0.00001711178,0.00008193352,0.0003967643,0.00002440788,0.002464378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007536939,"threshold_uncertainty_score":0.002521396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05076298688994845,"score_gpt":0.2677628770819094,"score_spread":0.216999890191961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}