{"id":"W4383679996","doi":"10.1016/j.jconrel.2023.07.003","title":"Supramolecular nanoarchitectonics of phenolic-based nanofiller for controlled diffusion of versatile drugs in hydrogels","year":2023,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Hydrogels: synthesis, properties, applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Fundamental Research Funds for the Central Universities; National Key Research and Development Program of China; Sichuan Province Science and Technology Support Program; State Key Laboratory of Polymer Materials Engineering; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China; China Postdoctoral Science Foundation; 1000 Talents Sichuan Program","keywords":"Self-healing hydrogels; Drug delivery; Controlled release; Nanotechnology; Drug; Chemistry; Lidocaine; Materials science; Biomedical engineering; Pharmacology; Medicine; Surgery; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001165755,0.0002316506,0.001151122,0.0004128503,0.00005697394,0.00001134639,0.0003814372,0.000264167,0.00002371021],"category_scores_gemma":[0.001479295,0.0001814888,0.0008101652,0.0003205595,0.0001423809,0.000007852418,0.00005839106,0.0001816871,0.000003115336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003661338,"about_ca_system_score_gemma":0.000519606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002246337,"about_ca_topic_score_gemma":0.000009333365,"domain_scores_codex":[0.9974023,0.0002679194,0.001373931,0.000239654,0.0003903445,0.0003258895],"domain_scores_gemma":[0.9975222,0.000332717,0.001108813,0.0004334233,0.0004679159,0.0001348826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01570338,0.0004290731,0.0001823299,0.00008211077,0.0003634687,0.000005449921,0.0001739806,0.005079315,0.9756783,0.00007221175,0.0002393161,0.001991014],"study_design_scores_gemma":[0.08951275,0.001250142,0.0001499562,0.0001833192,0.0003412514,0.00000942475,0.0002436673,0.02091327,0.8809334,0.0002624134,0.005916536,0.0002838682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939587,0.001518281,0.002291687,0.0005655131,0.0000950782,0.001349411,0.0000452337,0.000008593508,0.00016748],"genre_scores_gemma":[0.9982198,0.0002501017,0.0009032442,0.0001201736,0.00008547625,0.0001754137,0.00002418622,0.0000462619,0.0001753302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09474496,"threshold_uncertainty_score":0.74009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009185087179674,"score_gpt":0.2456799688565011,"score_spread":0.2364948816768271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}