{"id":"W4383684021","doi":"10.58931/cect.2023.2122","title":"Genetics of retinal degeneration in 2023","year":2023,"lang":"en","type":"article","venue":"Canadian Eye Care Today","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"RPE65; Genetic testing; Retinal degeneration; Disease; Retinal; Medicine; Bioinformatics; Genetics; Biology; Gene; Pathology; Genetic enhancement; Ophthalmology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002316606,0.0006291104,0.0003294575,0.001489353,0.0008598501,0.0008142933,0.0004039341,0.001277388,0.004417067],"category_scores_gemma":[0.000317582,0.0001658024,0.0004044743,0.001106478,0.0007772319,0.0002821809,0.0004443548,0.0004809389,0.001177172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003019365,"about_ca_system_score_gemma":0.002050571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.1117125,"about_ca_topic_score_gemma":0.07614638,"domain_scores_codex":[0.9997113,0.00003431137,0.00002267367,0.00004185826,0.0001309946,0.00005883739],"domain_scores_gemma":[0.9998875,0.00002152523,0.00002588296,0.00000477161,0.00003221505,0.0000281212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009663264,0.00023358,0.1142641,0.001265032,0.0003289877,0.1996795,0.002556217,0.0009349125,0.1707164,0.05980868,0.07798827,0.3712581],"study_design_scores_gemma":[0.00009812503,0.0002793836,0.2676077,0.001200067,0.0003644768,0.2877414,0.00121575,0.000772351,0.02001864,0.01199888,0.4085712,0.000131949],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.331211,0.3203751,0.008318089,0.02406424,0.001548953,0.0002995345,0.004408086,0.0007738321,0.3090011],"genre_scores_gemma":[0.78934,0.1086454,0.007543809,0.007631474,0.0006620843,0.00007730832,0.002235469,0.0001238726,0.08374062],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.1117125,"threshold_uncertainty_score":0.2221245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007617526973127096,"score_gpt":0.2376311859108728,"score_spread":0.2300136589377458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}