{"id":"W4383710651","doi":"10.15252/embr.202256150","title":"RNA polymerase II CTD is dispensable for transcription and required for termination in human cells","year":2023,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"College of Natural Resources and Sciences, Humboldt State University; Institut National Du Cancer; CNIB; Centre National de la Recherche Scientifique; Bundesministerium für Bildung und Forschung; Agence Nationale de la Recherche","keywords":"CTD; RNA polymerase II; Transcription (linguistics); Biology; Cell biology; Mutant; Molecular biology; Gene; Genetics; Gene expression; Promoter","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001989702,0.0002199752,0.0004689553,0.0003289466,0.0002277348,0.000942154,0.000237496,0.0002782842,0.002328336],"category_scores_gemma":[0.0003990621,0.0002676777,0.0001983006,0.0003281251,0.0004508497,0.0001541839,0.0001886918,0.0003857704,0.001058104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000328557,"about_ca_system_score_gemma":0.0003356237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001268715,"about_ca_topic_score_gemma":0.0009311076,"domain_scores_codex":[0.9997613,0.00003927379,0.00003416783,0.00006884566,0.00005280171,0.00004355844],"domain_scores_gemma":[0.9995055,0.0001694625,0.00008616094,0.00009853335,0.00003731475,0.0001030795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004984851,0.00001314821,0.001679182,0.00003571953,0.00001164772,0.0004205515,0.00002933275,0.00007898143,0.9952495,0.0002854828,0.0001541378,0.001543711],"study_design_scores_gemma":[0.00008427817,0.0001635839,0.02136455,0.00001446628,0.00004190263,0.003311799,0.00008627382,0.001244999,0.9660184,0.0003486078,0.007309183,0.00001192918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895941,0.003581438,0.002906985,0.0001329737,0.0000544388,0.000014342,0.001526454,0.0001268487,0.002062529],"genre_scores_gemma":[0.9964101,0.0003759124,0.0007228557,0.00004251328,0.00001575422,0.000007976088,0.001450963,0.00004469389,0.0009292656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002328336,"threshold_uncertainty_score":0.007789075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01207656518939135,"score_gpt":0.2630228260959643,"score_spread":0.2509462609065729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}