{"id":"W4383722655","doi":"10.3390/cancers15143552","title":"Phase 4 Multinational Multicenter Retrospective and Prospective Real-World Study of Nivolumab in Recurrent and Metastatic Squamous Cell Carcinoma of the Head and Neck","year":2023,"lang":"en","type":"article","venue":"Cancers","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; London Health Sciences Centre; Western University; University of British Columbia","funders":"","keywords":"Medicine; Nivolumab; Nausea; Prospective cohort study; Retrospective cohort study; Internal medicine; Oncology; Surgery; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006471621,0.0007687261,0.0008279312,0.0003068993,0.0005819247,0.0007616226,0.0007096548,0.0007562299,0.001220359],"category_scores_gemma":[0.003122814,0.0005704138,0.001110071,0.0005187475,0.0007316103,0.0006969785,0.0005392891,0.0009582503,0.0003413691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001029798,"about_ca_system_score_gemma":0.002200472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002248483,"about_ca_topic_score_gemma":0.005983999,"domain_scores_codex":[0.9980691,0.001358313,0.00009853955,0.0001777001,0.000164139,0.0001322105],"domain_scores_gemma":[0.9978275,0.0003798777,0.0006863368,0.0003833572,0.0003176673,0.0004052334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3534311,0.0326914,0.53746,0.00082652,0.004995503,0.0005577244,0.0006954622,0.003120548,0.01556376,0.0002505105,0.00419364,0.0462139],"study_design_scores_gemma":[0.1105786,0.2606435,0.605274,0.00009587456,0.003186583,0.001014289,0.0007975519,0.002730291,0.00420949,0.0002857638,0.01104494,0.0001391755],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959499,0.0005486005,0.0002748946,0.00009208332,0.00002852665,0.001581978,0.001137567,0.00001336887,0.0003731637],"genre_scores_gemma":[0.9894728,0.0004597977,0.002019185,0.0004374727,0.00006823822,0.003107999,0.003790722,0.00001406095,0.0006296954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006471621,"threshold_uncertainty_score":0.03422558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02954279433316932,"score_gpt":0.3391308171595348,"score_spread":0.3095880228263655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}