{"id":"W4383736226","doi":"10.3390/vetsci10070445","title":"Early-Life Exposure to Lipopolysaccharide Induces Persistent Changes in Gene Expression Profiles in the Liver and Spleen of Female FVB/N Mice","year":2023,"lang":"en","type":"article","venue":"Veterinary Sciences","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Alberta Prion Research Institute; Alberta Livestock and Meat Agency; University of Alberta","keywords":"TLR2; Chemokine; Spleen; TLR4; Cytokine; Biology; CXCL5; Immunology; Lipopolysaccharide; Endocrinology; Internal medicine; Medicine; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001844737,0.0005154875,0.000403044,0.0007979361,0.0001976221,0.000318745,0.0001569264,0.0003710844,0.001593646],"category_scores_gemma":[0.0001263203,0.0002771922,0.0003717037,0.0002731711,0.0004379859,0.0002585363,0.0002206482,0.0009767268,0.0006003135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002479306,"about_ca_system_score_gemma":0.0001892497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004928908,"about_ca_topic_score_gemma":0.0008535856,"domain_scores_codex":[0.9997391,0.00002093399,0.00001714568,0.00009011962,0.00006047553,0.00007224505],"domain_scores_gemma":[0.999739,0.0000187412,0.00009125037,0.0000205476,0.00003292151,0.00009750843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006771564,0.00008151905,0.0009096034,0.00002338986,0.000005831148,0.00006091925,0.00002549458,0.00001917048,0.9974799,0.00001999176,0.00002964797,0.0006674694],"study_design_scores_gemma":[0.0001503554,0.004053327,0.1722263,0.00004521369,0.0000884066,0.0009418142,0.0005267339,0.0008164376,0.8179808,0.0002323692,0.002900469,0.00003774101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947408,0.0009489976,0.001591432,0.0001514454,0.00004051101,0.00003105722,0.001613366,0.00006433078,0.0008180972],"genre_scores_gemma":[0.9837156,0.00154855,0.003200425,0.0003280512,0.00003157087,0.0002324628,0.002713819,0.00008297978,0.008146527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001593646,"threshold_uncertainty_score":0.005331278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05887112188372579,"score_gpt":0.2778544018915542,"score_spread":0.2189832800078285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}