{"id":"W4383872867","doi":"10.1128/mbio.00753-23","title":"Single-strain behavior predicts responses to environmental pH and osmolality in the gut microbiota","year":2023,"lang":"en","type":"article","venue":"mBio","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Killam Trusts; Crohn's and Colitis Canada; Universities Space Research Association; Auris Health; Canadian Institute for Advanced Research; Michael Smith Health Research BC; National Science Foundation","keywords":"Gut flora; Strain (injury); Microbiology; Biology; Chemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004670217,0.0003146887,0.0004714985,0.0005788907,0.0001718325,0.0006486381,0.0001502282,0.0003755342,0.0009684492],"category_scores_gemma":[0.001054097,0.0001697842,0.0003084186,0.0004822736,0.0002397481,0.0003480839,0.00033832,0.000294823,0.0003197799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001503611,"about_ca_system_score_gemma":0.0001225064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00112437,"about_ca_topic_score_gemma":0.0009095268,"domain_scores_codex":[0.9997072,0.00005913304,0.00002317022,0.00009340465,0.00007129936,0.00004592724],"domain_scores_gemma":[0.9992894,0.0001815764,0.0002350876,0.00006620475,0.0001307614,0.00009694656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004440644,0.0001206476,0.4223257,0.0001126694,0.0001522588,0.0001031692,0.0001269419,0.002515527,0.5626871,0.00006613692,0.0001632956,0.01118251],"study_design_scores_gemma":[0.000004968154,0.0005335697,0.9333189,0.00001612123,0.00005424586,0.0003490883,0.0003270566,0.01123978,0.05352961,0.0002519722,0.0003518477,0.00002283652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974363,0.0002437268,0.001495947,0.00003376747,0.00000685534,0.000009828637,0.0005231408,0.00001883308,0.000231489],"genre_scores_gemma":[0.9979296,0.0001192879,0.001279524,0.00002138901,0.000004750256,0.00001297414,0.0004614751,0.000009620905,0.0001614035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00112437,"threshold_uncertainty_score":0.00323981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02264597973774949,"score_gpt":0.2727877480307897,"score_spread":0.2501417682930402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}