{"id":"W4383874542","doi":"10.1016/j.euo.2023.05.013","title":"Long-term Outcomes of Chemoradiation for Muscle-invasive Bladder Cancer in Noncystectomy Candidates. Final Results of NRG Oncology RTOG 0524—A Phase 1/2 Trial of Paclitaxel + Trastuzumab with Daily Radiation or Paclitaxel Alone with Daily Irradiation","year":2023,"lang":"en","type":"article","venue":"European Urology Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"National Cancer Institute; NRG Oncology","keywords":"Medicine; Cystectomy; Internal medicine; Oncology; Clinical endpoint; Radiation therapy; Trastuzumab; Bladder cancer; Toxicity; Paclitaxel; Chemotherapy; Urology; Randomized controlled trial; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009785995,0.0004032943,0.001596182,0.0006674956,0.00006564219,0.00000511995,0.0002111068,0.0002995424,0.00008061225],"category_scores_gemma":[0.0005584615,0.0002974799,0.0001566207,0.0007639519,0.000462352,0.0001434984,0.00004495868,0.0003052327,0.00001003512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005046809,"about_ca_system_score_gemma":0.002279754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006076083,"about_ca_topic_score_gemma":0.004362128,"domain_scores_codex":[0.9962798,0.0007243338,0.001393789,0.0006979902,0.0003434104,0.0005607216],"domain_scores_gemma":[0.9963521,0.001216659,0.0014128,0.0004791538,0.0003784903,0.0001608156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7193693,0.006444022,0.1265706,0.0006078171,0.002373277,0.001066144,0.009036885,0.0008305417,0.007953371,0.00003160111,0.001630083,0.1240864],"study_design_scores_gemma":[0.3580105,0.06741992,0.5695612,0.00008957105,0.00114579,0.00007152083,0.0002899169,0.0001947792,0.001913831,0.0000133867,0.001037067,0.0002524215],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916383,0.0002888021,0.0002019569,0.002069102,0.0004332037,0.003013647,0.000966154,0.00005983203,0.001329002],"genre_scores_gemma":[0.9969083,0.0004978973,0.0003859768,0.0003537716,0.0002745887,0.0003762353,0.0007182014,0.00008876191,0.0003962515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4429906,"threshold_uncertainty_score":0.9999477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0508917166551936,"score_gpt":0.3631017691669565,"score_spread":0.3122100525117629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}