{"id":"W4383894929","doi":"10.1016/j.bbapap.2023.140930","title":"Bothrops atrox venom: Biochemical properties and cellular phenotypes of three highly toxic classes of toxins","year":2023,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics","topic":"Venomous Animal Envenomation and Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Medical Research Council; Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Venom; Proteases; Envenomation; Biology; Snake venom; Bothrops; Myotoxin; Toxin; Viability assay; Biochemistry; Cytotoxicity; Phenotype; Cell biology; Enzyme; Cell; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001735629,0.0002817621,0.0004120338,0.00008558145,0.0001284812,0.00003338255,0.0001925916,0.0001910749,0.000003269813],"category_scores_gemma":[0.00006626267,0.0002373117,0.0001162856,0.0001967137,0.0004921869,0.00001456948,0.0003429615,0.0001207436,0.000002839811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009553571,"about_ca_system_score_gemma":0.00009241357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000519873,"about_ca_topic_score_gemma":0.0000177007,"domain_scores_codex":[0.9986485,0.00005585119,0.0003995443,0.0004485346,0.0001720238,0.0002755254],"domain_scores_gemma":[0.9992165,0.00001434694,0.0002513957,0.0003233796,0.0001092009,0.00008516927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002442811,0.0001298668,0.00005134576,0.0003347036,0.0001386153,9.264323e-7,0.0002597604,0.000002251402,0.9978307,0.0005670687,0.0001417516,0.0002987094],"study_design_scores_gemma":[0.000489783,0.00100425,0.002220283,0.00008284442,0.00004868516,0.000003351105,0.0001634961,0.0001512538,0.9947777,0.0003806886,0.0003954958,0.0002821591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967917,0.001067948,0.0001485417,0.000807354,0.00003965689,0.000827126,0.0001154481,0.00003499201,0.0001672276],"genre_scores_gemma":[0.996433,0.001062394,0.002019393,0.00005842128,0.0001235816,0.00009110925,0.0000700076,0.00004002711,0.0001020946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00305301,"threshold_uncertainty_score":0.9677291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02426029107589838,"score_gpt":0.2291733337219297,"score_spread":0.2049130426460313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}