{"id":"W4383894929","doi":"10.1016/j.bbapap.2023.140930","title":"Bothrops atrox venom: Biochemical properties and cellular phenotypes of three highly toxic classes of toxins","year":2023,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics","topic":"Venomous Animal Envenomation and Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Medical Research Council; Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Venom; Proteases; Envenomation; Biology; Snake venom; Bothrops; Myotoxin; Toxin; Viability assay; Biochemistry; Cytotoxicity; Phenotype; Cell biology; Enzyme; Cell; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009467841,0.000363636,0.0002445357,0.0003725729,0.0001707599,0.0003376585,0.0001397566,0.0004111346,0.0005791975],"category_scores_gemma":[0.000131989,0.000130426,0.0003544024,0.0002530063,0.0002278814,0.0002814193,0.0002465347,0.0005163259,0.000194641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002054256,"about_ca_system_score_gemma":0.0001298621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005978281,"about_ca_topic_score_gemma":0.0005488325,"domain_scores_codex":[0.9998834,0.00001026003,0.0000157457,0.00001951474,0.0000395582,0.00003146506],"domain_scores_gemma":[0.9998513,0.00001643355,0.00005179967,0.00001443984,0.00002664644,0.00003920107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007913051,0.00001926605,0.0005296583,0.00001010548,0.000002809034,0.00007490184,0.00001295584,0.00001543549,0.99887,0.00002344816,0.000006822534,0.000355458],"study_design_scores_gemma":[0.00002418264,0.0009768762,0.1622428,0.000009798984,0.00006626939,0.003074855,0.0001905139,0.0007000912,0.8311934,0.0001720339,0.001336797,0.00001235058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974227,0.0005210673,0.0007257417,0.00006104976,0.000006474127,0.00002202325,0.0002535849,0.00001369812,0.0009738639],"genre_scores_gemma":[0.9957352,0.0004559953,0.00088291,0.00008876061,0.00001032705,0.00002388624,0.0007427587,0.000009830888,0.00205035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005978281,"threshold_uncertainty_score":0.001937628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02426029107589838,"score_gpt":0.2291733337219297,"score_spread":0.2049130426460313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}