{"id":"W4383895265","doi":"10.1016/s2352-3018(23)00170-4","title":"Lenacapavir: an attractive option, but proceed with caution","year":2023,"lang":"en","type":"letter","venue":"The Lancet HIV","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"AIDS Vancouver; University of British Columbia","funders":"","keywords":"Medicine; Regimen; Capsid; Dosing; Human immunodeficiency virus (HIV); Pharmacology; Internal medicine; Virology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002936046,0.001106998,0.001823121,0.0008074982,0.003072024,0.005191237,0.001739458,0.07532154,0.01022632],"category_scores_gemma":[0.01946439,0.0007078319,0.001832922,0.0004914236,0.003450318,0.0065309,0.001822377,0.05631902,0.01277744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002925573,"about_ca_system_score_gemma":0.003822034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004659876,"about_ca_topic_score_gemma":0.01008756,"domain_scores_codex":[0.99584,0.001240623,0.0003713981,0.0004978809,0.001553905,0.0004961466],"domain_scores_gemma":[0.9947055,0.002842641,0.0003855214,0.0001794696,0.0007803069,0.001106545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001102782,0.00004566427,0.0003365169,0.0000767485,0.00002604779,0.002153869,0.00008111183,0.0000921119,0.0002909312,0.005191258,0.9764856,0.01510983],"study_design_scores_gemma":[0.0002401236,0.00008771994,0.0005423889,0.0004941369,0.00002623324,0.002832122,0.0002843037,0.0004040891,0.0001699751,0.03322512,0.9616161,0.00007767051],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001591512,0.002328187,0.0001299469,0.9792885,0.01398966,0.000009507074,0.00003090007,0.00002433644,0.004039761],"genre_scores_gemma":[0.001506574,0.001273507,0.0002576171,0.9530209,0.03706245,0.00002397058,0.00001710441,0.00001728401,0.0068206],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.07532154,"threshold_uncertainty_score":0.03421038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05372274806631021,"score_gpt":0.2915391189057656,"score_spread":0.2378163708394554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}