{"id":"W4383910298","doi":"10.3390/curroncol30070480","title":"Strategic Insight into the Combination Therapies for Metastatic Colorectal Cancer","year":2023,"lang":"en","type":"review","venue":"Current Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Colorectal cancer; KRAS; Oncology; Internal medicine; Chemotherapy; Immunotherapy; Cancer; Adjuvant; Bioinformatics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002733969,0.0003033837,0.0007259054,0.00007433096,0.0001448365,0.00004177001,0.0003616047,0.0002341216,0.00001378332],"category_scores_gemma":[0.0001151937,0.0002062889,0.0003495063,0.0001604708,0.0001458878,0.000001665497,0.0001461352,0.0002090405,0.00001887099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001728374,"about_ca_system_score_gemma":0.001201147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003034588,"about_ca_topic_score_gemma":0.000789553,"domain_scores_codex":[0.998649,0.0001735351,0.0004144222,0.0004118375,0.00008713747,0.0002640718],"domain_scores_gemma":[0.9988526,0.0003626223,0.0003432,0.0002436556,0.0001433438,0.00005463853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002436985,0.0001413849,0.000003068303,0.002877594,0.0004306853,0.000001374747,0.0002497498,0.000004997202,0.0000436411,0.002108309,0.00455775,0.9895571],"study_design_scores_gemma":[0.0004294502,0.0005199822,0.000003077745,0.0003905278,0.0006479669,0.000004938327,0.00007686144,0.00002585556,0.00002369182,0.001290131,0.9963481,0.000239393],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005960538,0.9943166,0.0001040863,0.0001475836,0.002968,0.001448687,0.0002556559,0.00001466808,0.0001487009],"genre_scores_gemma":[0.0001724188,0.994709,0.00005304369,0.00005111767,0.0007358673,0.002656241,0.001443926,0.00006320107,0.0001151558],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9917904,"threshold_uncertainty_score":0.8412218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1982634518923017,"score_gpt":0.4541761677683733,"score_spread":0.2559127158760716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}