{"id":"W4383910298","doi":"10.3390/curroncol30070480","title":"Strategic Insight into the Combination Therapies for Metastatic Colorectal Cancer","year":2023,"lang":"en","type":"review","venue":"Current Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Colorectal cancer; KRAS; Oncology; Internal medicine; Chemotherapy; Immunotherapy; Cancer; Adjuvant; Bioinformatics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004998956,0.0006273902,0.0008302321,0.001443462,0.0002213809,0.0008658461,0.0005982461,0.0007380293,0.003213424],"category_scores_gemma":[0.0004728689,0.0002360622,0.0005005951,0.001114348,0.0003202635,0.001111454,0.0005680348,0.001816281,0.001443034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004771952,"about_ca_system_score_gemma":0.0006535929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006162537,"about_ca_topic_score_gemma":0.001363298,"domain_scores_codex":[0.9998502,0.00003756918,0.00001767083,0.00002507348,0.00005325265,0.00001623402],"domain_scores_gemma":[0.9998487,0.00007618905,0.00001901303,0.000004616278,0.00003859435,0.00001279259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00009446754,0.0001074556,0.0001979867,0.01546601,0.0001035579,0.0003447481,0.00009037292,0.0004670733,0.00411139,0.008705069,0.02573912,0.9445729],"study_design_scores_gemma":[0.00002200333,0.0001467279,0.0004361646,0.002064947,0.0000925511,0.001212582,0.00004326888,0.0001509194,0.000643583,0.002031574,0.9931426,0.0000131018],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002012024,0.9972495,0.0002891405,0.0004704957,0.0002035567,0.000009127223,0.00002030813,0.000008367714,0.001548193],"genre_scores_gemma":[0.001455803,0.9968232,0.0004180984,0.0003633086,0.0001461878,0.00001430025,0.00003628108,0.000002171888,0.0007406598],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003213424,"threshold_uncertainty_score":0.01075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1982634518923017,"score_gpt":0.4541761677683733,"score_spread":0.2559127158760716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}