{"id":"W4384008411","doi":"10.15252/embr.202256512","title":"MOV10 recruits DCP2 to decap human LINE‐1 RNA by forming large cytoplasmic granules with phase separation properties","year":2023,"lang":"en","type":"article","venue":"EMBO Reports","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine; National Natural Science Foundation of China; Massachusetts Department of Agricultural Resources","keywords":"RNA; Cell biology; RNA interference; Biology; Cytoplasm; Effector; Chemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003521203,0.0001496155,0.0001465418,0.00008107886,0.0002412731,0.00005980013,0.00008977184,0.00008478248,0.00001524556],"category_scores_gemma":[0.00008808268,0.0001176964,0.0000449743,0.0002075265,0.00002667812,0.00001248389,0.00008894953,0.00008621802,0.00002073323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001804263,"about_ca_system_score_gemma":0.00007869466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004980588,"about_ca_topic_score_gemma":0.0002473578,"domain_scores_codex":[0.9986268,0.00002974094,0.0002682393,0.0004020015,0.0002488267,0.0004244331],"domain_scores_gemma":[0.9992628,0.000004266603,0.00009213424,0.0003592845,0.0001213104,0.0001602158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000792381,0.00006114665,0.000807294,0.00002129927,0.00003275318,0.0001700147,0.0001254501,0.00004813233,0.979148,0.000009313714,0.0175826,0.001914779],"study_design_scores_gemma":[0.0005218184,0.0007420661,0.0001783672,0.00005233572,0.00001000324,0.000121663,0.0001790621,0.0001905131,0.9530277,0.00002272677,0.04473031,0.0002234436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974737,0.0002324504,0.0008097372,0.0001782317,0.00007171289,0.0004366548,0.00001458475,0.00005397007,0.0007289505],"genre_scores_gemma":[0.9804415,0.00003114126,0.000112332,0.00009874091,0.0001333334,0.0001411914,0.000408713,0.00003133552,0.01860176],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02714771,"threshold_uncertainty_score":0.479952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02961585310336641,"score_gpt":0.3426340342194456,"score_spread":0.3130181811160792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}