{"id":"W4384008411","doi":"10.15252/embr.202256512","title":"MOV10 recruits DCP2 to decap human LINE‐1 RNA by forming large cytoplasmic granules with phase separation properties","year":2023,"lang":"en","type":"article","venue":"EMBO Reports","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine; National Natural Science Foundation of China; Massachusetts Department of Agricultural Resources","keywords":"RNA; Cell biology; RNA interference; Biology; Cytoplasm; Effector; Chemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183233,0.0004348201,0.0001895176,0.0001199205,0.0001398976,0.000335346,0.0002652708,0.0003206264,0.001412065],"category_scores_gemma":[0.0001220598,0.0001800865,0.000220599,0.00005871431,0.0002013174,0.0001774187,0.0004303575,0.0003545583,0.0009543147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002749782,"about_ca_system_score_gemma":0.0001495362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000350393,"about_ca_topic_score_gemma":0.0005964437,"domain_scores_codex":[0.9998734,0.00001820884,0.000006219931,0.00004039629,0.00003330974,0.00002851647],"domain_scores_gemma":[0.9999154,0.00001254617,0.0000183014,0.00000850729,0.000005747335,0.00003948864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006665344,0.00001130357,0.0002012798,0.00001940636,0.000002910864,0.00006948446,0.000008779836,0.00002219946,0.9989098,0.00004503031,0.00004522699,0.0005978749],"study_design_scores_gemma":[0.00001697093,0.00009287201,0.004466608,0.000003049012,0.00000349413,0.0003666795,0.00002162324,0.0009268819,0.991766,0.00002357025,0.002308154,0.000003934093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937019,0.001001131,0.003160407,0.0001253251,0.00003005693,0.00002909391,0.0001312877,0.0001104968,0.00171021],"genre_scores_gemma":[0.9908351,0.0003933217,0.003869266,0.0001274838,0.00001478919,0.00003552289,0.0006249674,0.00004863226,0.004050904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001412065,"threshold_uncertainty_score":0.004723847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02961585310336641,"score_gpt":0.3426340342194456,"score_spread":0.3130181811160792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}