{"id":"W4384008720","doi":"10.1038/s41598-023-38354-9","title":"Midgut transcriptomic responses to dengue and chikungunya viruses in the vectors Aedes albopictus and Aedes malayensis","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canada Research Chairs; University Health Network","funders":"National Medical Research Council; Duke-NUS Medical School; Medical Research Council; Ministry of Education - Singapore; Ministry of Education, India; Agence Nationale de la Recherche","keywords":"Arbovirus; Chikungunya; Aedes albopictus; Biology; Dengue fever; Virology; Aedes; Midgut; Anopheles; Vector (molecular biology); Transcriptome; Dengue virus; Aedes aegypti; Gene; Virus; Malaria; Genetics; Immunology; Gene expression; Larva; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006943836,0.0002678623,0.0002287129,0.0002904731,0.0001966619,0.0002475858,0.00006467042,0.0001978713,0.0008841968],"category_scores_gemma":[0.0001198221,0.0001097166,0.0003243261,0.000233898,0.0001317442,0.0002032633,0.0002450494,0.0002940409,0.0002805486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001780724,"about_ca_system_score_gemma":0.0001693596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001421238,"about_ca_topic_score_gemma":0.002065895,"domain_scores_codex":[0.9999264,0.000005108466,0.000004480935,0.00002802901,0.00001660441,0.00001928078],"domain_scores_gemma":[0.9999408,0.000009846647,0.0000171849,0.000003531687,0.00001610318,0.0000126642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001857028,0.0000143734,0.007466163,0.000137987,0.00001681482,0.00007262946,0.00008286426,0.00007664378,0.9888797,0.0000403107,0.0001024849,0.00292441],"study_design_scores_gemma":[0.000009774097,0.0003403447,0.8977591,0.0000387198,0.0001049314,0.0006203765,0.000410736,0.001501765,0.09508046,0.0001541607,0.003958215,0.00002145992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922719,0.001458119,0.0006606882,0.00006187611,0.00001849791,0.00001581051,0.004747231,0.00002275594,0.0007432208],"genre_scores_gemma":[0.979133,0.001868674,0.001988154,0.000147583,0.00002161286,0.00008040159,0.01293243,0.00002463377,0.003803617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001421238,"threshold_uncertainty_score":0.00295794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02355917901390208,"score_gpt":0.295122578562339,"score_spread":0.2715633995484369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}